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DOC2A has not been detected as a mutational cancer driver

DOC2A
Ensembl id ENSG00000149927
Mutated samples
Coding Sequence 67 (1.0%)
Protein Affecting 12 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all DOC2A gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 24 5 1.36
Serous ovarian adenocarcinoma No 2 2 0.63
Bladder carcinoma No 1 1 1.02
Breast carcinoma No 8 1 0.09
Uterine corpus endometrioid carcinoma No 3 1 0.43
Head and neck squamous cell carcinoma No 2 1 0.27
Esophageal carcinoma No 3 1 0.68
Lung adenocarcinoma No 5 0 0.00
Acute myeloid leukemia No 2 0 0.00
Medulloblastoma No 1 0 0.00
Lung squamous cell carcinoma No 3 0 0.00
Renal clear cell carcinoma No 1 0 0.00
Thyroid carcinoma No 1 0 0.00
Lower grade glioma No 2 0 0.00
Stomach adenocarcinoma No 5 0 0.00
Small cell lung carcinoma No 1 0 0.00
Colorectal adenocarcinoma No 2 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence