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DDX60 has not been detected as a mutational cancer driver

DDX60
Ensembl id ENSG00000137628
Mutated samples
Coding Sequence 116 (1.7%)
Protein Affecting 79 (1.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all DDX60 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 50 36 9.76
Lung adenocarcinoma No 8 6 1.53
Bladder carcinoma No 5 4 4.08
Lung squamous cell carcinoma No 10 4 2.30
Uterine corpus endometrioid carcinoma No 6 4 1.74
Stomach adenocarcinoma No 6 4 2.48
Head and neck squamous cell carcinoma No 5 4 1.07
Small cell lung carcinoma No 3 3 4.35
Neuroblastoma No 3 2 0.95
Colorectal adenocarcinoma No 4 2 0.87
Diffuse B cell lymphoma No 2 2 8.70
Glioblastoma multiforme No 2 2 0.53
Prostate adenocarcinoma No 2 1 0.41
Hepatocarcinoma No 2 1 1.11
Acute myeloid leukemia No 1 1 0.51
Breast carcinoma No 1 1 0.09
Pancreas adenocarcinoma No 2 1 0.47
Esophageal carcinoma No 1 1 0.68
Chronic lymphocytic leukemia No 1 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence