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DDAH2 has not been detected as a mutational cancer driver

DDAH2
Ensembl id ENSG00000213722
Mutated samples
Coding Sequence 57 (0.8%)
Protein Affecting 11 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all DDAH2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 19 5 1.36
Stomach adenocarcinoma No 8 2 1.24
Lung adenocarcinoma No 5 1 0.26
Lung squamous cell carcinoma No 5 1 0.57
Head and neck squamous cell carcinoma No 4 1 0.27
Esophageal carcinoma No 4 1 0.68
Prostate adenocarcinoma No 1 0 0.00
Hepatocarcinoma No 1 0 0.00
Bladder carcinoma No 1 0 0.00
Breast carcinoma No 2 0 0.00
Uterine corpus endometrioid carcinoma No 3 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Lower grade glioma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
Glioblastoma multiforme No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence