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COL5A1 has not been detected as a mutational cancer driver

COL5A1
Ensembl id ENSG00000130635
Mutated samples
Coding Sequence 229 (3.4%)
Protein Affecting 163 (2.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all COL5A1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 77 61 16.53
Lung adenocarcinoma No 17 15 3.84
Esophageal carcinoma No 16 14 9.59
Stomach adenocarcinoma No 17 11 6.83
Uterine corpus endometrioid carcinoma No 12 10 4.35
Breast carcinoma No 13 9 0.78
Head and neck squamous cell carcinoma No 12 9 2.40
Lung squamous cell carcinoma No 12 7 4.02
Bladder carcinoma No 7 4 4.08
Glioblastoma multiforme No 8 4 1.06
Hepatocarcinoma No 4 3 3.33
Renal clear cell carcinoma No 3 3 0.72
Thyroid carcinoma No 5 3 0.93
Prostate adenocarcinoma No 3 2 0.82
Pancreas adenocarcinoma No 2 2 0.93
Colorectal adenocarcinoma No 6 2 0.87
Neuroblastoma No 1 1 0.48
Lower grade glioma No 2 1 0.59
Serous ovarian adenocarcinoma No 3 1 0.32
Small cell lung carcinoma No 1 1 1.45
Chronic lymphocytic leukemia No 3 0 0.00
Pylocytic astrocytoma No 5 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence