COL4A3 has not been detected as a mutational cancer driver
| COL4A3 |
|---|
| Ensembl id ENSG00000169031 |
| Mutated samples
Coding Sequence 121 (1.8%) Protein Affecting 93 (1.4%) |
| Mode of action Unclassified |
| Known driver No |
| Cancer type | Signals (Biases) |
|---|
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all COL4A3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.
| Cancer type | Driver | Mutated samples (CS) | Mutated samples (PAM) | % Mutated samples (PAM) |
|---|---|---|---|---|
| Cutaneous melanoma | No | 46 | 40 | 10.84 |
| Lung squamous cell carcinoma | No | 9 | 8 | 4.60 |
| Head and neck squamous cell carcinoma | No | 9 | 6 | 1.60 |
| Lung adenocarcinoma | No | 8 | 5 | 1.28 |
| Bladder carcinoma | No | 7 | 5 | 5.10 |
| Uterine corpus endometrioid carcinoma | No | 8 | 5 | 2.17 |
| Renal clear cell carcinoma | No | 4 | 4 | 0.96 |
| Small cell lung carcinoma | No | 4 | 4 | 5.80 |
| Stomach adenocarcinoma | No | 6 | 3 | 1.86 |
| Breast carcinoma | No | 3 | 2 | 0.17 |
| Neuroblastoma | No | 2 | 2 | 0.95 |
| Chronic lymphocytic leukemia | No | 2 | 2 | 0.69 |
| Prostate adenocarcinoma | No | 2 | 1 | 0.41 |
| Thyroid carcinoma | No | 1 | 1 | 0.31 |
| Multiple myeloma | No | 1 | 1 | 1.45 |
| Serous ovarian adenocarcinoma | No | 1 | 1 | 0.32 |
| Glioblastoma multiforme | No | 1 | 1 | 0.26 |
| Esophageal carcinoma | No | 5 | 1 | 0.68 |
| Acute lymphocytic leukemia | No | 1 | 1 | 0.82 |
| Lower grade glioma | No | 1 | 0 | 0.00 |
Choose a transcript:
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.
| Variant Locus | Samples | AA pos | AA change | Consequence |
|---|