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COL4A3 has not been detected as a mutational cancer driver

COL4A3
Ensembl id ENSG00000169031
Mutated samples
Coding Sequence 121 (1.8%)
Protein Affecting 93 (1.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all COL4A3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 46 40 10.84
Lung squamous cell carcinoma No 9 8 4.60
Head and neck squamous cell carcinoma No 9 6 1.60
Lung adenocarcinoma No 8 5 1.28
Bladder carcinoma No 7 5 5.10
Uterine corpus endometrioid carcinoma No 8 5 2.17
Renal clear cell carcinoma No 4 4 0.96
Small cell lung carcinoma No 4 4 5.80
Stomach adenocarcinoma No 6 3 1.86
Breast carcinoma No 3 2 0.17
Neuroblastoma No 2 2 0.95
Chronic lymphocytic leukemia No 2 2 0.69
Prostate adenocarcinoma No 2 1 0.41
Thyroid carcinoma No 1 1 0.31
Multiple myeloma No 1 1 1.45
Serous ovarian adenocarcinoma No 1 1 0.32
Glioblastoma multiforme No 1 1 0.26
Esophageal carcinoma No 5 1 0.68
Acute lymphocytic leukemia No 1 1 0.82
Lower grade glioma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence