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COL3A1 has not been detected as a mutational cancer driver

COL3A1
Ensembl id ENSG00000168542
Mutated samples
Coding Sequence 194 (2.9%)
Protein Affecting 159 (2.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all COL3A1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 76 63 17.07
Lung adenocarcinoma No 30 27 6.91
Lung squamous cell carcinoma No 12 12 6.90
Head and neck squamous cell carcinoma No 15 12 3.20
Glioblastoma multiforme No 9 8 2.11
Colorectal adenocarcinoma No 7 6 2.62
Uterine corpus endometrioid carcinoma No 7 5 2.17
Serous ovarian adenocarcinoma No 4 4 1.27
Esophageal carcinoma No 5 4 2.74
Breast carcinoma No 5 3 0.26
Prostate adenocarcinoma No 4 2 0.82
Renal clear cell carcinoma No 4 2 0.48
Neuroblastoma No 2 2 0.95
Chronic lymphocytic leukemia No 4 2 0.69
Stomach adenocarcinoma No 3 2 1.24
Pancreas adenocarcinoma No 1 1 0.47
Thyroid carcinoma No 1 1 0.31
Multiple myeloma No 1 1 1.45
Lower grade glioma No 2 1 0.59
Small cell lung carcinoma No 1 1 1.45
Non small cell lung carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence