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CEP192 has not been detected as a mutational cancer driver

CEP192
Ensembl id ENSG00000101639
Mutated samples
Coding Sequence 110 (1.6%)
Protein Affecting 81 (1.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CEP192 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 21 13 3.52
Lung adenocarcinoma No 13 11 2.81
Lung squamous cell carcinoma No 12 10 5.75
Breast carcinoma No 11 9 0.78
Stomach adenocarcinoma No 10 6 3.73
Small cell lung carcinoma No 6 6 8.70
Uterine corpus endometrioid carcinoma No 8 4 1.74
Serous ovarian adenocarcinoma No 4 4 1.27
Head and neck squamous cell carcinoma No 8 4 1.07
Esophageal carcinoma No 4 4 2.74
Thyroid carcinoma No 3 3 0.93
Hepatocarcinoma No 3 2 2.22
Bladder carcinoma No 2 1 1.02
Pancreas adenocarcinoma No 1 1 0.47
Renal clear cell carcinoma No 1 1 0.24
Neuroblastoma No 1 1 0.48
Diffuse B cell lymphoma No 1 1 4.35
Chronic lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence