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CACNA1I has not been detected as a mutational cancer driver

CACNA1I
Ensembl id ENSG00000100346
Mutated samples
Coding Sequence 133 (2.0%)
Protein Affecting 93 (1.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CACNA1I gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 48 36 9.76
Lung squamous cell carcinoma No 13 11 6.32
Lung adenocarcinoma No 11 6 1.53
Head and neck squamous cell carcinoma No 11 6 1.60
Uterine corpus endometrioid carcinoma No 7 5 2.17
Stomach adenocarcinoma No 7 5 3.11
Hepatocarcinoma No 5 4 4.44
Breast carcinoma No 6 4 0.35
Renal clear cell carcinoma No 5 4 0.96
Glioblastoma multiforme No 4 3 0.79
Colorectal adenocarcinoma No 2 2 0.87
Esophageal carcinoma No 3 2 1.37
Prostate adenocarcinoma No 2 1 0.41
Bladder carcinoma No 2 1 1.02
Chronic lymphocytic leukemia No 3 1 0.34
Multiple myeloma No 1 1 1.45
Lower grade glioma No 1 1 0.59
Neuroblastoma No 1 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence