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BRSK1 has not been detected as a mutational cancer driver

BRSK1
Ensembl id ENSG00000160469
Mutated samples
Coding Sequence 76 (1.1%)
Protein Affecting 45 (0.7%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all BRSK1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 18 10 2.71
Lung squamous cell carcinoma No 6 6 3.45
Head and neck squamous cell carcinoma No 10 6 1.60
Stomach adenocarcinoma No 7 5 3.11
Uterine corpus endometrioid carcinoma No 6 4 1.74
Lung adenocarcinoma No 8 3 0.77
Breast carcinoma No 4 3 0.26
Serous ovarian adenocarcinoma No 3 2 0.63
Esophageal carcinoma No 2 2 1.37
Hepatocarcinoma No 1 1 1.11
Thyroid carcinoma No 1 1 0.31
Colorectal adenocarcinoma No 3 1 0.44
Glioblastoma multiforme No 2 1 0.26
Prostate adenocarcinoma No 1 0 0.00
Bladder carcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Lower grade glioma No 1 0 0.00
Acute lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence