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BRCA1 is detected as a mutational cancer driver

BRCA1 reports

Gene details
BRCA1
Ensembl ID ENSG00000012048
Transcript ID ENST00000471181
Protein ID ENSP00000418960
Cancer types where is driver 2
Cohorts where is driver 4
Mutated samples 45
Mutations 400
Mode of action Loss of function
Known driver True
Method signals per Cancer Type
Cancer type Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
combination Combination
Mutation distribution
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Consequence