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BMP1 has not been detected as a mutational cancer driver

BMP1
Ensembl id ENSG00000168487
Mutated samples
Coding Sequence 81 (1.2%)
Protein Affecting 37 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all BMP1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 26 8 2.17
Uterine corpus endometrioid carcinoma No 9 8 3.48
Breast carcinoma No 7 4 0.35
Lung adenocarcinoma No 4 3 0.77
Stomach adenocarcinoma No 6 3 1.86
Renal clear cell carcinoma No 2 2 0.48
Serous ovarian adenocarcinoma No 2 2 0.63
Small cell lung carcinoma No 2 2 2.90
Esophageal carcinoma No 5 2 1.37
Neuroblastoma No 2 1 0.48
Lower grade glioma No 2 1 0.59
Colorectal adenocarcinoma No 2 1 0.44
Hepatocarcinoma No 1 0 0.00
Bladder carcinoma No 2 0 0.00
Medulloblastoma No 1 0 0.00
Thyroid carcinoma No 1 0 0.00
Multiple myeloma No 1 0 0.00
Head and neck squamous cell carcinoma No 2 0 0.00
Glioblastoma multiforme No 4 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence