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BCR has not been detected as a mutational cancer driver

BCR
Ensembl id ENSG00000186716
Mutated samples
Coding Sequence 52 (0.8%)
Protein Affecting 36 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all BCR gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 23 15 4.07
Stomach adenocarcinoma No 5 4 2.48
Lung adenocarcinoma No 3 3 0.77
Chronic lymphocytic leukemia No 4 3 1.03
Breast carcinoma No 2 2 0.17
Diffuse B cell lymphoma No 2 2 8.70
Prostate adenocarcinoma No 1 1 0.41
Lung squamous cell carcinoma No 2 1 0.57
Renal clear cell carcinoma No 1 1 0.24
Uterine corpus endometrioid carcinoma No 2 1 0.43
Multiple myeloma No 1 1 1.45
Serous ovarian adenocarcinoma No 1 1 0.32
Head and neck squamous cell carcinoma No 2 1 0.27
Lower grade glioma No 1 0 0.00
Pylocytic astrocytoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence