IntOGen - BARD1 gene cancer mutations

BARD1 is detected as a mutational cancer driver

BARD1 reports

Methods
Mutation distribution

Gene details

BARD1
Ensembl ID ENSG00000138376 Transcript ID ENST00000260947 Protein ID ENSP00000260947
Cancer types where is driver 1 Cohorts where is driver 1 Mutated samples 4 Mutations 270
Mode of action Activating
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence