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ATXN1 has not been detected as a mutational cancer driver

ATXN1
Ensembl id ENSG00000124788
Mutated samples
Coding Sequence 89 (1.3%)
Protein Affecting 53 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ATXN1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 27 17 4.61
Lung adenocarcinoma No 8 7 1.79
Breast carcinoma No 13 6 0.52
Stomach adenocarcinoma No 6 5 3.11
Head and neck squamous cell carcinoma No 7 4 1.07
Uterine corpus endometrioid carcinoma No 4 3 1.30
Esophageal carcinoma No 3 3 2.05
Renal clear cell carcinoma No 3 2 0.48
Hepatocarcinoma No 2 1 1.11
Bladder carcinoma No 1 1 1.02
Lower grade glioma No 2 1 0.59
Small cell lung carcinoma No 2 1 1.45
Colorectal adenocarcinoma No 2 1 0.44
Glioblastoma multiforme No 2 1 0.26
Medulloblastoma No 1 0 0.00
Thyroid carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 3 0 0.00
Multiple myeloma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence