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ATP12A has not been detected as a mutational cancer driver

ATP12A
Ensembl id ENSG00000075673
Mutated samples
Coding Sequence 113 (1.7%)
Protein Affecting 76 (1.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ATP12A gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 43 25 6.78
Breast carcinoma No 8 6 0.52
Head and neck squamous cell carcinoma No 9 6 1.60
Lung adenocarcinoma No 8 5 1.28
Lung squamous cell carcinoma No 5 4 2.30
Renal clear cell carcinoma No 5 4 0.96
Uterine corpus endometrioid carcinoma No 4 4 1.74
Stomach adenocarcinoma No 6 4 2.48
Bladder carcinoma No 3 3 3.06
Colorectal adenocarcinoma No 4 3 1.31
Multiple myeloma No 2 2 2.90
Serous ovarian adenocarcinoma No 2 2 0.63
Small cell lung carcinoma No 2 2 2.90
Glioblastoma multiforme No 3 2 0.53
Prostate adenocarcinoma No 1 1 0.41
Pancreas adenocarcinoma No 1 1 0.47
Lower grade glioma No 1 1 0.59
Esophageal carcinoma No 1 1 0.68
Neuroblastoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
Acute lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence