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ASTN2 has not been detected as a mutational cancer driver

ASTN2
Ensembl id ENSG00000148219
Mutated samples
Coding Sequence 225 (3.3%)
Protein Affecting 126 (1.9%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ASTN2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 66 37 10.03
Lung adenocarcinoma No 26 21 5.37
Lung squamous cell carcinoma No 21 17 9.77
Stomach adenocarcinoma No 15 11 6.83
Head and neck squamous cell carcinoma No 15 9 2.40
Colorectal adenocarcinoma No 7 6 2.62
Breast carcinoma No 9 5 0.44
Uterine corpus endometrioid carcinoma No 13 5 2.17
Renal clear cell carcinoma No 6 3 0.72
Serous ovarian adenocarcinoma No 3 3 0.95
Esophageal carcinoma No 6 3 2.05
Pancreas adenocarcinoma No 1 1 0.47
Non small cell lung carcinoma No 2 1 3.23
Multiple myeloma No 2 1 1.45
Lower grade glioma No 4 1 0.59
Glioblastoma multiforme No 4 1 0.26
Acute lymphocytic leukemia No 1 1 0.82
Prostate adenocarcinoma No 1 0 0.00
Hepatocarcinoma No 3 0 0.00
Bladder carcinoma No 3 0 0.00
Thyroid carcinoma No 2 0 0.00
Neuroblastoma No 1 0 0.00
Chronic lymphocytic leukemia No 12 0 0.00
Pylocytic astrocytoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence