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AQP6 has not been detected as a mutational cancer driver

AQP6
Ensembl id ENSG00000086159
Mutated samples
Coding Sequence 40 (0.6%)
Protein Affecting 18 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all AQP6 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 15 7 1.90
Head and neck squamous cell carcinoma No 5 3 0.80
Prostate adenocarcinoma No 1 1 0.41
Lung adenocarcinoma No 1 1 0.26
Breast carcinoma No 2 1 0.09
Lung squamous cell carcinoma No 3 1 0.57
Thyroid carcinoma No 2 1 0.31
Uterine corpus endometrioid carcinoma No 1 1 0.43
Stomach adenocarcinoma No 2 1 0.62
Esophageal carcinoma No 3 1 0.68
Hepatocarcinoma No 1 0 0.00
Acute myeloid leukemia No 1 0 0.00
Medulloblastoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Multiple myeloma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence