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API5 has not been detected as a mutational cancer driver

API5
Ensembl id ENSG00000166181
Mutated samples
Coding Sequence 33 (0.5%)
Protein Affecting 26 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all API5 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung squamous cell carcinoma No 6 4 2.30
Stomach adenocarcinoma No 4 4 2.48
Breast carcinoma No 3 3 0.26
Cutaneous melanoma No 5 3 0.81
Uterine corpus endometrioid carcinoma No 4 3 1.30
Lung adenocarcinoma No 2 2 0.51
Hepatocarcinoma No 1 1 1.11
Bladder carcinoma No 2 1 1.02
Neuroblastoma No 1 1 0.48
Lower grade glioma No 1 1 0.59
Serous ovarian adenocarcinoma No 1 1 0.32
Head and neck squamous cell carcinoma No 1 1 0.27
Glioblastoma multiforme No 1 1 0.26
Prostate adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence