ANXA1 has not been detected as a mutational cancer driver
| ANXA1 |
|---|
| Ensembl id ENSG00000135046 |
| Mutated samples
Coding Sequence 20 (0.3%) Protein Affecting 14 (0.2%) |
| Mode of action Unclassified |
| Known driver No |
| Cancer type | Signals (Biases) |
|---|
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ANXA1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.
| Cancer type | Driver | Mutated samples (CS) | Mutated samples (PAM) | % Mutated samples (PAM) |
|---|---|---|---|---|
| Cutaneous melanoma | No | 5 | 3 | 0.81 |
| Lower grade glioma | No | 2 | 2 | 1.18 |
| Stomach adenocarcinoma | No | 3 | 2 | 1.24 |
| Bladder carcinoma | No | 1 | 1 | 1.02 |
| Breast carcinoma | No | 1 | 1 | 0.09 |
| Lung squamous cell carcinoma | No | 1 | 1 | 0.57 |
| Small cell lung carcinoma | No | 1 | 1 | 1.45 |
| Colorectal adenocarcinoma | No | 1 | 1 | 0.44 |
| Head and neck squamous cell carcinoma | No | 1 | 1 | 0.27 |
| Acute lymphocytic leukemia | No | 1 | 1 | 0.82 |
| Lung adenocarcinoma | No | 1 | 0 | 0.00 |
| Thyroid carcinoma | No | 1 | 0 | 0.00 |
| Chronic lymphocytic leukemia | No | 1 | 0 | 0.00 |
Choose a transcript:
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.
| Variant Locus | Samples | AA pos | AA change | Consequence |
|---|