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ANPEP has not been detected as a mutational cancer driver

ANPEP
Ensembl id ENSG00000166825
Mutated samples
Coding Sequence 94 (1.4%)
Protein Affecting 67 (1.0%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ANPEP gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 26 16 4.34
Renal clear cell carcinoma No 10 9 2.16
Lung squamous cell carcinoma No 9 8 4.60
Uterine corpus endometrioid carcinoma No 11 7 3.04
Breast carcinoma No 6 6 0.52
Lung adenocarcinoma No 7 4 1.02
Bladder carcinoma No 3 3 3.06
Colorectal adenocarcinoma No 3 3 1.31
Serous ovarian adenocarcinoma No 3 2 0.63
Glioblastoma multiforme No 3 2 0.53
Esophageal carcinoma No 2 2 1.37
Hepatocarcinoma No 1 1 1.11
Neuroblastoma No 1 1 0.48
Stomach adenocarcinoma No 3 1 0.62
Small cell lung carcinoma No 1 1 1.45
Head and neck squamous cell carcinoma No 3 1 0.27
Chronic lymphocytic leukemia No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence