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ANKS1B has not been detected as a mutational cancer driver

ANKS1B
Ensembl id ENSG00000185046
Mutated samples
Coding Sequence 172 (2.5%)
Protein Affecting 90 (1.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ANKS1B gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 48 27 7.32
Lung adenocarcinoma No 19 13 3.32
Lung squamous cell carcinoma No 16 12 6.90
Breast carcinoma No 10 6 0.52
Head and neck squamous cell carcinoma No 10 6 1.60
Esophageal carcinoma No 9 6 4.11
Renal clear cell carcinoma No 6 4 0.96
Uterine corpus endometrioid carcinoma No 7 4 1.74
Prostate adenocarcinoma No 2 2 0.82
Multiple myeloma No 2 2 2.90
Stomach adenocarcinoma No 5 2 1.24
Colorectal adenocarcinoma No 4 2 0.87
Hepatocarcinoma No 3 1 1.11
Bladder carcinoma No 5 1 1.02
Pancreas adenocarcinoma No 1 1 0.47
Chronic lymphocytic leukemia No 16 1 0.34
Medulloblastoma No 2 0 0.00
Thyroid carcinoma No 1 0 0.00
Pylocytic astrocytoma No 4 0 0.00
Small cell lung carcinoma No 1 0 0.00
Glioblastoma multiforme No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence