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ANKHD1 has not been detected as a mutational cancer driver

ANKHD1
Ensembl id ENSG00000131503
Mutated samples
Coding Sequence 134 (2.0%)
Protein Affecting 102 (1.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ANKHD1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 33 28 7.59
Head and neck squamous cell carcinoma No 13 11 2.93
Uterine corpus endometrioid carcinoma No 10 9 3.91
Lung adenocarcinoma No 10 7 1.79
Bladder carcinoma No 8 7 7.14
Lung squamous cell carcinoma No 7 7 4.02
Renal clear cell carcinoma No 12 6 1.44
Breast carcinoma No 5 5 0.44
Stomach adenocarcinoma No 9 5 3.11
Serous ovarian adenocarcinoma No 6 4 1.27
Colorectal adenocarcinoma No 4 4 1.75
Hepatocarcinoma No 3 2 2.22
Lower grade glioma No 2 2 1.18
Thyroid carcinoma No 1 1 0.31
Multiple myeloma No 2 1 1.45
Glioblastoma multiforme No 1 1 0.26
Esophageal carcinoma No 3 1 0.68
Acute lymphocytic leukemia No 1 1 0.82
Prostate adenocarcinoma No 1 0 0.00
Neuroblastoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Small cell lung carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence