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ANGPTL5 has not been detected as a mutational cancer driver

ANGPTL5
Ensembl id ENSG00000187151
Mutated samples
Coding Sequence 45 (0.7%)
Protein Affecting 29 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ANGPTL5 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 14 9 2.44
Lung squamous cell carcinoma No 5 5 2.87
Stomach adenocarcinoma No 4 3 1.86
Lung adenocarcinoma No 4 2 0.51
Small cell lung carcinoma No 2 2 2.90
Bladder carcinoma No 1 1 1.02
Breast carcinoma No 2 1 0.09
Non small cell lung carcinoma No 1 1 3.23
Chronic lymphocytic leukemia No 2 1 0.34
Serous ovarian adenocarcinoma No 2 1 0.32
Colorectal adenocarcinoma No 2 1 0.44
Glioblastoma multiforme No 2 1 0.26
Esophageal carcinoma No 1 1 0.68
Prostate adenocarcinoma No 1 0 0.00
Uterine corpus endometrioid carcinoma No 1 0 0.00
Head and neck squamous cell carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence