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AKAP7 has not been detected as a mutational cancer driver

AKAP7
Ensembl id ENSG00000118507
Mutated samples
Coding Sequence 32 (0.5%)
Protein Affecting 18 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all AKAP7 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Stomach adenocarcinoma No 6 5 3.11
Cutaneous melanoma No 6 3 0.81
Small cell lung carcinoma No 2 2 2.90
Head and neck squamous cell carcinoma No 3 2 0.53
Lung adenocarcinoma No 1 1 0.26
Breast carcinoma No 1 1 0.09
Lung squamous cell carcinoma No 1 1 0.57
Renal clear cell carcinoma No 1 1 0.24
Pylocytic astrocytoma No 2 1 0.99
Colorectal adenocarcinoma No 1 1 0.44
Prostate adenocarcinoma No 1 0 0.00
Bladder carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
Serous ovarian adenocarcinoma No 2 0 0.00
Esophageal carcinoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence