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AKAP6 has not been detected as a mutational cancer driver

AKAP6
Ensembl id ENSG00000151320
Mutated samples
Coding Sequence 213 (3.1%)
Protein Affecting 154 (2.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all AKAP6 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 55 38 10.30
Lung adenocarcinoma No 20 15 3.84
Lung squamous cell carcinoma No 15 15 8.62
Breast carcinoma No 14 13 1.13
Head and neck squamous cell carcinoma No 13 12 3.20
Uterine corpus endometrioid carcinoma No 12 10 4.35
Esophageal carcinoma No 11 10 6.85
Stomach adenocarcinoma No 14 8 4.97
Colorectal adenocarcinoma No 8 6 2.62
Bladder carcinoma No 6 5 5.10
Serous ovarian adenocarcinoma No 5 4 1.27
Acute lymphocytic leukemia No 4 4 3.28
Renal clear cell carcinoma No 6 3 0.72
Small cell lung carcinoma No 4 3 4.35
Glioblastoma multiforme No 3 3 0.79
Lower grade glioma No 2 2 1.18
Prostate adenocarcinoma No 2 1 0.41
Hepatocarcinoma No 1 1 1.11
Neuroblastoma No 1 1 0.48
Thyroid carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 13 0 0.00
Multiple myeloma No 2 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence