Top
ADCY8 has not been detected as a mutational cancer driver

ADCY8
Ensembl id ENSG00000155897
Mutated samples
Coding Sequence 234 (3.4%)
Protein Affecting 167 (2.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ADCY8 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 79 53 14.36
Lung adenocarcinoma No 28 20 5.12
Head and neck squamous cell carcinoma No 19 18 4.80
Lung squamous cell carcinoma No 17 11 6.32
Stomach adenocarcinoma No 15 11 6.83
Uterine corpus endometrioid carcinoma No 10 9 3.91
Breast carcinoma No 12 8 0.70
Esophageal carcinoma No 13 8 5.48
Renal clear cell carcinoma No 6 6 1.44
Small cell lung carcinoma No 6 6 8.70
Colorectal adenocarcinoma No 7 5 2.18
Prostate adenocarcinoma No 7 4 1.65
Bladder carcinoma No 2 2 2.04
Glioblastoma multiforme No 3 2 0.53
Hepatocarcinoma No 1 1 1.11
Pancreas adenocarcinoma No 1 1 0.47
Thyroid carcinoma No 2 1 0.31
Non small cell lung carcinoma No 2 1 3.23
Chronic lymphocytic leukemia No 2 0 0.00
Lower grade glioma No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence