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ADAM2 has not been detected as a mutational cancer driver

ADAM2
Ensembl id ENSG00000104755
Mutated samples
Coding Sequence 123 (1.8%)
Protein Affecting 86 (1.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ADAM2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 47 32 8.67
Lung squamous cell carcinoma No 14 12 6.90
Head and neck squamous cell carcinoma No 10 9 2.40
Lung adenocarcinoma No 13 8 2.05
Bladder carcinoma No 4 4 4.08
Breast carcinoma No 6 3 0.26
Small cell lung carcinoma No 3 3 4.35
Colorectal adenocarcinoma No 3 3 1.31
Renal clear cell carcinoma No 2 2 0.48
Chronic lymphocytic leukemia No 3 2 0.69
Serous ovarian adenocarcinoma No 3 2 0.63
Stomach adenocarcinoma No 3 2 1.24
Glioblastoma multiforme No 4 2 0.53
Non small cell lung carcinoma No 2 1 3.23
Esophageal carcinoma No 3 1 0.68
Prostate adenocarcinoma No 1 0 0.00
Hepatocarcinoma No 1 0 0.00
Uterine corpus endometrioid carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence