ERCC2 is detected as a mutational cancer driver
ERCC2 reports
Gene details
ERCC2 |
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Ensembl ID
ENSG00000104884
Transcript ID ENST00000391945 Protein ID ENSP00000375809 |
Cancer types where is driver
1
Cohorts where is driver 6 Mutated samples 74 Mutations 243 |
Mode of action Loss of function |
Known driver False |
Method signals per Cancer Type
Cancer type | Methods | Samples | Samples (%) |
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In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
---|---|---|---|
BLCA (Bladder cancer) | 61 | 45 | 73.77 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Consequence |
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