Gene Symbol Cohort Driver by any method CGC gene Methods in which is called as driver Intogen tier Intogen driver Post- processing filter ABCB1 ICGC_WGS_ESCA_ESAD_UK_2019 TRUE FALSE dndscv, cbase 3 TRUE Warning artifact ABI1 ICGC_WGS_ESCA_ESAD_UK_2019 FALSE ADGRB1 HARTWIG_WGS_ANSC_2020 FALSE AFF3 HARTWIG_WGS_BRCA_2020 FALSE ALB ICGC_WXS_HCC_LICA_FR_2019 TRUE FALSE dndscv, cbase, mutpanning 1 TRUE Warning artifact ALB PCAWG_WGS_LIVER_HCC TRUE FALSE dndscv, mutpanning 1 TRUE Warning artifact BMPR2 TCGA_WXS_STAD TRUE FALSE mutpanning 1 FALSE No driver CARS1 ICGC_WXS_STAD_GACA_CN_2019 TRUE FALSE combination 1 FALSE No driver CBFA2T3 HARTWIG_WGS_UCEC_2020 FALSE CR1 ICGC_WXS_AML_LAML_KR_VARSCAN_2019 TRUE FALSE oncodriveclustl, smregions 1 TRUE Warning artifact CR1 OTHER_WGS_MM_NATLEUK2018 TRUE FALSE oncodriveclustl, smregions, cbase, mutpanning 1 TRUE Warning artifact DAZAP1 CBIOP_WXS_DLBCL_DFCI_2018 TRUE FALSE oncodrivefml, cbase 1 TRUE Warning artifact DNAJB1 HARTWIG_WGS_BLCA_2020 FALSE EHD2 HARTWIG_WGS_PRAD_2020 TRUE FALSE cbase 1 FALSE No driver EML4 TCGA_WXS_ESCA FALSE EML4 HARTWIG_WGS_SCLC_2020 FALSE ENPEP HARTWIG_WGS_SBC_2020 FALSE ERG TCGA_WXS_OVT FALSE ERG CBIOP_WXS_PRAD_MSKCC_DCFI_2018_MET FALSE EXT2 ICGC_WXS_CHOL_BTCA_JP_2019 FALSE FAM186A OTHER_WGS_DLBCL_NATCOM_2018 TRUE FALSE hotmaps 1 FALSE No driver FAM186A ICGC_WXS_WDTC_THCA_SA_2019 FALSE FANCA CBIOP_WXS_VSC_CUK_2018 FALSE FBLN1 HARTWIG_WGS_SBC_2020 FALSE FOXD4L1 OTHER_WGS_MM_NATLEUK2018 TRUE FALSE smregions 1 FALSE No driver GATA1 ICGC_WGS_BRCA_BRCA_FR_2019 FALSE HERC2 ICGC_WXS_WDTC_THCA_SA_2019 FALSE HGF HARTWIG_WGS_SBC_2020 FALSE H4C9 ICGC_WGS_CLLSLL_CLLE_ES_2019 TRUE TRUE combination 4 FALSE No driver HOXA11 TCGA_WXS_UCEC FALSE HOXD13 HARTWIG_WGS_BRCA_2020 FALSE HOXD13 ICGC_WGS_ESCA_ESAD_UK_2019 FALSE HTRA2 HARTWIG_WGS_SBC_2020 FALSE IFNAR1 OTHER_WGS_MM_NATLEUK2018 FALSE IFNGR1 TCGA_WXS_CESC TRUE FALSE oncodrivefml, cbase 1 TRUE Lack of literature evidence INO80 OTHER_WGS_DLBCL_NATCOM_2018 TRUE FALSE cbase 3 FALSE No driver KDM5A TCGA_WXS_MEL FALSE KEL TCGA_WXS_LGGNOS TRUE FALSE cbase 3 FALSE No driver KIFC1 HARTWIG_WGS_UCEC_2020 TRUE FALSE combination 1 FALSE No driver KLHL36 OTHER_WGS_MM_NATLEUK2018 FALSE LOX HARTWIG_WGS_SBC_2020 FALSE LPAR4 TCGA_WXS_HNSC TRUE FALSE oncodrivefml 3 FALSE No driver LPP CBIOP_WXS_HNSC_BROAD FALSE LPP TCGA_WXS_UCS FALSE LY75-CD302 TCGA_WXS_AML TRUE FALSE smregions 3 FALSE No driver MALT1 OTHER_WGS_DLBCL_NATCOM_2018 FALSE MAP2 HARTWIG_WGS_LNM_2020 TRUE FALSE cbase 3 FALSE No driver MCM3AP HARTWIG_WGS_HNSC_2020 FALSE MTCP1 TCGA_WXS_COADREAD FALSE NCOA1 HARTWIG_WGS_BRCA_2020 FALSE NEFH ICGC_WXS_WDTC_THCA_SA_2019 TRUE FALSE combination 4 FALSE No driver NKTR TCGA_WXS_AML TRUE FALSE oncodriveclustl 4 FALSE No driver NONO HARTWIG_WGS_BRCA_2020 FALSE NONO HARTWIG_WGS_MEL_2020 FALSE NPEPPS OTHER_WXS_AML_PRY_BEAT_2018 TRUE FALSE oncodriveclustl, smregions, mutpanning, hotmaps 1 TRUE Warning artifact NPEPPS ICGC_WXS_LUSC_LUSC_KR_2019 TRUE FALSE oncodriveclustl, smregions, hotmaps 3 TRUE Warning artifact NPM1 TCGA_WXS_AML FALSE NRP1 ICGC_WXS_AML_LAML_KR_2019 TRUE FALSE oncodriveclustl, smregions 1 TRUE Lack of literature evidence PAK2 ICGC_WXS_WDTC_THCA_SA_2019 FALSE PCDH17 ICGC_WXS_CHOL_BTCA_JP_2019 TRUE FALSE oncodrivefml, cbase 1 TRUE Warning artifact PDPR ICGC_WXS_WDTC_THCA_SA_2019 FALSE PLCB4 TCGA_WXS_UM TRUE FALSE oncodriveclustl, smregions, hotmaps 1 TRUE Warning artifact PPT2 ICGC_WXS_BLCA_BLCA_CN_2019 TRUE FALSE oncodriveclustl, cbase, hotmaps 1 TRUE Warning artifact PRF1 HARTWIG_WGS_NSCLC_2020 FALSE PRF1 TCGA_WXS_STAD FALSE PRR14 ICGC_WXS_WDTC_THCA_SA_2019 FALSE PRRX1 TCGA_WXS_STAD FALSE RABEP1 HARTWIG_WGS_CSCC_2020 FALSE RALGDS HARTWIG_WGS_CSCC_2020 FALSE RARA HARTWIG_WGS_SBC_2020 FALSE RBFOX2 ICGC_WXS_WDTC_THCA_SA_2019 FALSE RGL3 OTHER_WXS_AML_PRY_BEAT_2018 TRUE FALSE smregions 3 FALSE No driver RSPH10B2 STJUDE_WGS_D_LGG_2018 TRUE FALSE oncodriveclustl, smregions, cbase 1 TRUE Warning artifact SATB1 HARTWIG_WGS_SBC_2020 FALSE SDC4 TCGA_WXS_STAD FALSE SEPTIN9 OTHER_WGS_MM_NATLEUK2018 FALSE SET HARTWIG_WGS_SCLC_2020 FALSE SFMBT2 OTHER_WGS_PBCA_DE_MB FALSE SLC45A3 ICGC_WGS_MEL_SKCA_BR_2019 FALSE STRN HARTWIG_WGS_PRAD_2020 FALSE TCIRG1 TCGA_WXS_MEL FALSE UBE2D2 OTHER_WGS_PBCA_DE_MB FALSE UGT2B17 PCAWG_WGS_OVARY_ADENOCA TRUE FALSE dndscv, cbase 1 TRUE Warning artifact USP44 HARTWIG_WGS_BCC_2020 FALSE USP44 HARTWIG_WGS_UCEC_2020 FALSE VAV1 PCAWG_WGS_PANC_ADENOCA FALSE WDR45 ICGC_WXS_BLCA_BLCA_CN_2019 TRUE FALSE oncodrivefml, dndscv, cbase 1 TRUE Warning artifact WNK4 OTHER_WGS_PBCA_DE_MB FALSE WRN OTHER_WXS_NPC_NATCOM2017 FALSE XPC ICGC_WXS_HCC_LICA_FR_2019 TRUE TRUE combination 4 FALSE No driver ZFX TCGA_WXS_MEL TRUE FALSE mutpanning 1 FALSE No driver ZNF148 HARTWIG_WGS_ESCA_2020 TRUE FALSE combination 3 FALSE No driver ZNF165 OTHER_WGS_PBCA_DE_MB FALSE