CTNNB1
UCEC
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Select a mutation to see further information
| Mutation | AA change | Consequence type | BoostDM score | IntOGen frequency |
|---|---|---|---|---|
| 3:41224610:T | S33F | missense_variant | 1.00 | 11 |
| 3:41224610:G | S33C | missense_variant | 1.00 | 10 |
| 3:41224622:T | S37F | missense_variant | 1.00 | 9 |
| 3:41224622:G | S37C | missense_variant | 1.00 | 9 |
| 3:41224634:T | T41I | missense_variant | 1.00 | 6 |
| 3:41224606:T | D32Y | missense_variant | 1.00 | 6 |
| 3:41224612:A | G34R | missense_variant | 1.00 | 6 |
| 3:41224610:A | S33Y | missense_variant | 1.00 | 5 |
| 3:41224606:A | D32N | missense_variant | 1.00 | 5 |
| 3:41224613:A | G34E | missense_variant | 1.00 | 5 |
| 3:41224613:T | G34V | missense_variant | 1.00 | 5 |
| 3:41224633:G | T41A | missense_variant | 1.00 | 4 |
| 3:41224646:T | S45F | missense_variant | 1.00 | 3 |
| 3:41224609:C | S33P | missense_variant | 1.00 | 3 |
| 3:41224621:G | S37A | missense_variant | 1.00 | 3 |
| 3:41224621:C | S37P | missense_variant | 1.00 | 2 |
| 3:41224607:C | D32A | missense_variant | 1.00 | 2 |
| 3:41224607:G | D32G | missense_variant | 1.00 | 2 |
| 3:41224612:C | G34R | missense_variant | 1.00 | 2 |
| 3:41224646:G | S45C | missense_variant | 1.00 | 1 |
| 3:41224645:C | S45P | missense_variant | 1.00 | 1 |
| 3:41224607:T | D32V | missense_variant | 1.00 | 1 |
| 3:41224606:C | D32H | missense_variant | 1.00 | 1 |
| 3:41224616:G | I35S | missense_variant | 1.00 | 1 |
| 3:41224622:A | S37Y | missense_variant | 1.00 | 0 |
| 3:41224634:G | T41S | missense_variant | 1.00 | 0 |
| 3:41224634:A | T41N | missense_variant | 1.00 | 0 |
| 3:41224646:A | S45Y | missense_variant | 1.00 | 0 |
| 3:41224633:C | T41P | missense_variant | 1.00 | 0 |
| 3:41224633:T | T41S | missense_variant | 1.00 | 0 |
| 3:41224642:A | P44T | missense_variant | 1.00 | 0 |
| 3:41224618:A | H36N | missense_variant | 1.00 | 0 |
| 3:41224618:G | H36D | missense_variant | 1.00 | 0 |
| 3:41224618:T | H36Y | missense_variant | 1.00 | 0 |
| 3:41224637:A | T42K | missense_variant | 1.00 | 0 |
| 3:41224637:G | T42R | missense_variant | 1.00 | 0 |
| 3:41224637:T | T42I | missense_variant | 1.00 | 0 |
| 3:41224640:A | A43D | missense_variant | 1.00 | 0 |
| 3:41224640:G | A43G | missense_variant | 1.00 | 0 |
| 3:41224640:T | A43V | missense_variant | 1.00 | 0 |
| 3:41224642:G | P44A | missense_variant | 1.00 | 0 |
| 3:41224642:T | P44S | missense_variant | 1.00 | 0 |
| 3:41224643:A | P44H | missense_variant | 1.00 | 0 |
| 3:41224643:G | P44R | missense_variant | 1.00 | 0 |
| 3:41224643:T | P44L | missense_variant | 1.00 | 0 |
| 3:41224645:A | S45T | missense_variant | 1.00 | 0 |
| 3:41224609:A | S33T | missense_variant | 1.00 | 0 |
| 3:41224645:G | S45A | missense_variant | 1.00 | 0 |
| 3:41224609:G | S33A | missense_variant | 1.00 | 0 |
| 3:41224621:A | S37T | missense_variant | 1.00 | 0 |
| 3:41224636:T | T42S | missense_variant | 1.00 | 0 |
| 3:41224619:G | H36R | missense_variant | 1.00 | 0 |
| 3:41224619:T | H36L | missense_variant | 1.00 | 0 |
| 3:41224630:C | T40P | missense_variant | 1.00 | 0 |
| 3:41224630:G | T40A | missense_variant | 1.00 | 0 |
| 3:41224630:T | T40S | missense_variant | 1.00 | 0 |
| 3:41224615:G | I35V | missense_variant | 1.00 | 0 |
| 3:41224615:T | I35F | missense_variant | 1.00 | 0 |
| 3:41224615:C | I35L | missense_variant | 1.00 | 0 |
| 3:41224619:C | H36P | missense_variant | 1.00 | 0 |
| 3:41224636:C | T42P | missense_variant | 1.00 | 0 |
| 3:41224636:G | T42A | missense_variant | 1.00 | 0 |
| 3:41224625:A | G38D | missense_variant | 1.00 | 0 |
| 3:41224625:T | G38V | missense_variant | 1.00 | 0 |
| 3:41224627:A | A39T | missense_variant | 1.00 | 0 |
| 3:41224627:C | A39P | missense_variant | 1.00 | 0 |
| 3:41224627:T | A39S | missense_variant | 1.00 | 0 |
| 3:41224613:C | G34A | missense_variant | 1.00 | 0 |
| 3:41224639:A | A43T | missense_variant | 1.00 | 0 |
| 3:41224639:C | A43P | missense_variant | 1.00 | 0 |
| 3:41224639:T | A43S | missense_variant | 1.00 | 0 |
| 3:41224624:A | G38S | missense_variant | 1.00 | 0 |
| 3:41224624:C | G38R | missense_variant | 1.00 | 0 |
| 3:41224624:T | G38C | missense_variant | 1.00 | 0 |
| 3:41224625:C | G38A | missense_variant | 1.00 | 0 |
| 3:41224616:C | I35T | missense_variant | 1.00 | 0 |
| 3:41224616:A | I35N | missense_variant | 1.00 | 0 |
| 3:41224628:T | A39V | missense_variant | 1.00 | 0 |
| 3:41224628:G | A39G | missense_variant | 1.00 | 0 |
| 3:41224628:A | A39D | missense_variant | 1.00 | 0 |
| 3:41224631:A | T40N | missense_variant | 1.00 | 0 |
| 3:41224631:G | T40S | missense_variant | 1.00 | 0 |
| 3:41224631:T | T40I | missense_variant | 1.00 | 0 |
| 3:41224617:G | I35M | missense_variant | 1.00 | 0 |
| 3:41224608:G | D32E | missense_variant | 1.00 | 0 |
| 3:41224620:G | H36Q | missense_variant | 1.00 | 0 |
| 3:41224620:A | H36Q | missense_variant | 1.00 | 0 |
| 3:41224608:A | D32E | missense_variant | 1.00 | 0 |
| 3:41224612:T | G34* | stop_gained | 1.00 | 0 |
In silico saturation mutagenesis
| Cancer type | Selected cancer type | Mutational discovery Index | Feature Complexity |
|---|---|---|---|
| (UCEC) Endometrial cancer | UCEC | 0.91 | 0.13 |