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CDH1 ST ×
Select a mutation to see further information
Mutation AA change Consequence type BoostDM score IntOGen frequency
16:68810269:T D254Y missense_variant 0.88 3
16:68813495:T K440N missense_variant 0.94 2
16:68813374:T D400V missense_variant 0.87 2
16:68808724:A V188D missense_variant 0.85 2
16:68808730:G Y190C missense_variant 0.80 2
16:68815581:T E463* stop_gained 1.00 1
16:68813495:A K440K splice_region_variant 1.00 1
16:68738318:T E24* stop_gained 1.00 1
16:68808448:T E138* stop_gained 0.99 1
16:68822081:T R598* stop_gained 0.99 1
16:68811714:T D288V missense_variant 0.98 1
16:68810279:G D257G missense_variant 0.98 1
16:68808796:A G212E missense_variant 0.96 1
16:68813379:C D402H missense_variant 0.94 1
16:68815567:T N458I missense_variant 0.89 1
16:68810278:A D257N missense_variant 0.88 1
16:68811857:A E336K missense_variant 0.86 1
16:68808736:A I192N missense_variant 0.85 1
16:68811801:C F317S missense_variant 0.85 1
16:68815555:A V454E missense_variant 0.69 1
16:68808731:A Y190* stop_gained 1.00 0
16:68808731:G Y190* stop_gained 1.00 0
16:68738315:T Q23* stop_gained 1.00 0
16:68812162:T Q346* stop_gained 1.00 0
16:68813364:T K397* stop_gained 1.00 0
16:68808442:T Q136* stop_gained 1.00 0
16:68808720:T K187* stop_gained 1.00 0
16:68738308:A W20* stop_gained 1.00 0
16:68808567:A Q177Q splice_region_variant 1.00 0
16:68819314:T E534* stop_gained 1.00 0
16:68815668:T R492* stop_gained 1.00 0
16:68738359:A Y37* stop_gained 1.00 0
16:68738359:G Y37* stop_gained 1.00 0
16:68819292:A W526* stop_gained 1.00 0
16:68819397:G Y561* stop_gained 1.00 0
16:68819397:A Y561* stop_gained 1.00 0
16:68808484:T R150* stop_gained 1.00 0
16:68828271:G Y754* stop_gained 1.00 0
16:68828271:A Y754* stop_gained 1.00 0
16:68819283:G Y523* stop_gained 1.00 0
16:68819283:A Y523* stop_gained 1.00 0
16:68815662:T E490* stop_gained 1.00 0
16:68833404:T E852* stop_gained 1.00 0
16:68801693:T R63* stop_gained 1.00 0
16:68808786:T R209* stop_gained 1.00 0
16:68815539:T Q449* stop_gained 1.00 0
16:68823566:T E702* stop_gained 1.00 0
16:68822210:T Q641* stop_gained 1.00 0
16:68819353:T E547* stop_gained 1.00 0
16:68811854:T R335* stop_gained 1.00 0
16:68808490:T Q152* stop_gained 1.00 0
16:68823485:T K675* stop_gained 1.00 0
16:68813422:A L416* stop_gained 1.00 0
16:68815704:T E504* stop_gained 1.00 0
16:68801726:T R74* stop_gained 1.00 0
16:68808825:T R222* stop_gained 1.00 0
16:68801732:T K76* stop_gained 1.00 0
16:68808436:T G134* stop_gained 1.00 0
16:68833413:T K855* stop_gained 1.00 0
16:68737461:T Q16* stop_gained 1.00 0
16:68801827:A Y107* stop_gained 1.00 0
16:68801827:G Y107* stop_gained 1.00 0
16:68801891:T Q129* stop_gained 1.00 0
16:68811739:G Y296* stop_gained 1.00 0
16:68811739:A Y296* stop_gained 1.00 0
16:68815665:T K491* stop_gained 1.00 0
16:68738314:A C22* stop_gained 1.00 0
16:68833408:A S853* stop_gained 1.00 0
16:68833408:G S853* stop_gained 1.00 0
16:68815701:T Q503* stop_gained 1.00 0
16:68823578:T Q706* stop_gained 1.00 0
16:68823551:T K697* stop_gained 1.00 0
16:68738307:A W20* stop_gained 1.00 0
16:68822098:A C603* stop_gained 1.00 0
16:68822111:T K608* stop_gained 1.00 0
16:68808744:T Q195* stop_gained 1.00 0
16:68808487:T R151* stop_gained 1.00 0
16:68801678:T E58* stop_gained 1.00 0
16:68810216:G S236* stop_gained 1.00 0
16:68810216:A S236* stop_gained 1.00 0
16:68738387:T E47* stop_gained 1.00 0
16:68801843:T K113* stop_gained 1.00 0
16:68813436:T G421* stop_gained 1.00 0
16:68808705:T K182* stop_gained 1.00 0
16:68738351:T E35* stop_gained 1.00 0
16:68808789:T E210* stop_gained 1.00 0
16:68815536:T Q448* stop_gained 1.00 0
16:68801789:T Q95* stop_gained 1.00 0
16:68810284:T K259* stop_gained 1.00 0
16:68815533:T K447* stop_gained 1.00 0
16:68801828:T R108* stop_gained 1.00 0
16:68833433:G Y861* stop_gained 1.00 0
16:68833433:A Y861* stop_gained 1.00 0
16:68738324:T E26* stop_gained 1.00 0
16:68812190:G L355* stop_gained 1.00 0
16:68812190:A L355* stop_gained 1.00 0
16:68808553:T K173* stop_gained 1.00 0
16:68801686:A C60* stop_gained 1.00 0
16:68808799:A W213* stop_gained 1.00 0
16:68819383:T K557* stop_gained 1.00 0
16:68823464:T K668* stop_gained 1.00 0
16:68819293:T R527* stop_gained 1.00 0
16:68813414:A Y413* stop_gained 1.00 0
16:68813414:G Y413* stop_gained 1.00 0
16:68828304:A Q765Q splice_region_variant 1.00 0
16:68808535:T E167* stop_gained 1.00 0
16:68828209:T R734* stop_gained 1.00 0
16:68833402:A S851* stop_gained 1.00 0
16:68833402:G S851* stop_gained 1.00 0
16:68812149:G Y341* stop_gained 1.00 0
16:68812149:A Y341* stop_gained 1.00 0
16:68808538:T K168* stop_gained 1.00 0
16:68822117:T Q610* stop_gained 1.00 0
16:68823419:T K653* stop_gained 1.00 0
16:68822099:T E604* stop_gained 1.00 0
16:68811859:A E336E splice_region_variant 1.00 0
16:68808804:T K215* stop_gained 1.00 0
16:68801696:T Q64* stop_gained 1.00 0
16:68810272:T Q255* stop_gained 1.00 0
16:68833296:T K816* stop_gained 1.00 0
16:68812177:T Q351* stop_gained 1.00 0
16:68823506:T E682* stop_gained 1.00 0
16:68828268:A Y753* stop_gained 1.00 0
16:68828268:G Y753* stop_gained 1.00 0
16:68811698:T E283* stop_gained 1.00 0
16:68823479:T Q673* stop_gained 1.00 0
16:68815725:T Q511* stop_gained 1.00 0
16:68808525:A C163* stop_gained 1.00 0
16:68819291:A W526* stop_gained 1.00 0
16:68823425:T K655* stop_gained 1.00 0
16:68823527:T E689* stop_gained 1.00 0
16:68808452:A L139* stop_gained 1.00 0
16:68738390:T R48* stop_gained 1.00 0
16:68823572:T G704* stop_gained 1.00 0
16:68823401:T Q647* stop_gained 1.00 0
16:68828231:A L741* stop_gained 1.00 0
16:68828231:G L741* stop_gained 1.00 0
16:68808845:A Y228* stop_gained 1.00 0
16:68808845:G Y228* stop_gained 1.00 0
16:68813439:T Q422* stop_gained 1.00 0
16:68812183:T E353* stop_gained 1.00 0
16:68810290:T E261* stop_gained 1.00 0
16:68815544:G Y450* stop_gained 1.00 0
16:68815544:A Y450* stop_gained 1.00 0
16:68808800:A W213* stop_gained 1.00 0
16:68828224:T E739* stop_gained 1.00 0
16:68833458:T K870* stop_gained 1.00 0
16:68801710:A Y68* stop_gained 1.00 0
16:68801710:G Y68* stop_gained 1.00 0
16:68811779:T E310* stop_gained 1.00 0
16:68815718:G Y508* stop_gained 1.00 0
16:68815718:A Y508* stop_gained 1.00 0
16:68828274:G Y755* stop_gained 1.00 0
16:68828274:A Y755* stop_gained 1.00 0
16:68815674:T E494* stop_gained 1.00 0
16:68738332:A C28* stop_gained 1.00 0
16:68737427:A W4* stop_gained 1.00 0
16:68737426:A W4* stop_gained 1.00 0
16:68833478:A Y876* stop_gained 1.00 0
16:68801809:G Y101* stop_gained 1.00 0
16:68801809:A Y101* stop_gained 1.00 0
16:68833478:G Y876* stop_gained 1.00 0
16:68810311:T K268* stop_gained 1.00 0
16:68833331:G Y827* stop_gained 1.00 0
16:68833331:A Y827* stop_gained 1.00 0
16:68811791:T K314* stop_gained 1.00 0
16:68823557:T Q699* stop_gained 1.00 0
16:68801802:A L99* stop_gained 1.00 0
16:68819374:T E554* stop_gained 1.00 0
16:68813403:T E410* stop_gained 1.00 0
16:68813316:T K381* stop_gained 1.00 0
16:68823547:A C695* stop_gained 1.00 0
16:68833427:G Y859* stop_gained 1.00 0
16:68833427:A Y859* stop_gained 1.00 0
16:68810302:T E265* stop_gained 1.00 0
16:68833355:A Y835* stop_gained 1.00 0
16:68833355:G Y835* stop_gained 1.00 0
16:68823437:T E659* stop_gained 1.00 0
16:68823520:A C686* stop_gained 1.00 0
16:68813337:T E388* stop_gained 1.00 0
16:68737441:A S9* stop_gained 1.00 0
16:68822215:A Y642* stop_gained 1.00 0
16:68822215:G Y642* stop_gained 1.00 0
16:68828242:T E745* stop_gained 1.00 0
16:68811757:G Y302* stop_gained 1.00 0
16:68811757:A Y302* stop_gained 1.00 0
16:68808813:T E218* stop_gained 1.00 0
16:68813322:T Q383* stop_gained 1.00 0
16:68813315:A Y380* stop_gained 1.00 0
16:68813315:G Y380* stop_gained 1.00 0
16:68829749:G Y797* stop_gained 1.00 0
16:68829749:A Y797* stop_gained 1.00 0
16:68810299:T Q264* stop_gained 1.00 0
16:68738408:T R54* stop_gained 1.00 0
16:68823526:A C688* stop_gained 1.00 0
16:68833371:T E841* stop_gained 0.99 0
16:68815746:T E518* stop_gained 0.99 0
16:68813484:T K437* stop_gained 0.99 0
16:68801831:T K109* stop_gained 0.99 0
16:68808496:T R154* stop_gained 0.99 0
16:68822075:T E596* stop_gained 0.99 0
16:68808565:T Q177* stop_gained 0.99 0
16:68810255:A L249* stop_gained 0.99 0
16:68828221:T K738* stop_gained 0.99 0
16:68808714:T E185* stop_gained 0.99 0
16:68829669:T Q771* stop_gained 0.99 0
16:68823451:A Y663* stop_gained 0.99 0
16:68823451:G Y663* stop_gained 0.99 0
16:68822174:T E629* stop_gained 0.99 0
16:68801814:A W103* stop_gained 0.99 0
16:68823576:A L705* stop_gained 0.99 0
16:68801762:T K86* stop_gained 0.99 0
16:68813331:T E386* stop_gained 0.99 0
16:68815749:T Q519* stop_gained 0.99 0
16:68808696:T K179* stop_gained 0.99 0
16:68811770:T Q307* stop_gained 0.99 0
16:68833440:T E864* stop_gained 0.99 0
16:68829795:T E813* stop_gained 0.99 0
16:68829780:T G808* stop_gained 0.99 0
16:68823491:T Q677* stop_gained 0.99 0
16:68819365:T E551* stop_gained 0.99 0
16:68808493:T K153* stop_gained 0.99 0
16:68819310:A W532* stop_gained 0.99 0
16:68819309:A W532* stop_gained 0.99 0
16:68811857:T E336* stop_gained 0.99 0
16:68815527:T E445* stop_gained 0.99 0
16:68828281:T E758* stop_gained 0.99 0
16:68813493:T K440* stop_gained 0.99 0
16:68823404:T E648* stop_gained 0.98 0
16:68823605:T G715* stop_gained 0.98 0
16:68829664:A L769* stop_gained 0.98 0
16:68828302:T Q765* stop_gained 0.98 0
16:68808529:T E165* stop_gained 0.98 0
16:68810248:T E247* stop_gained 0.98 0
16:68828192:A L728* stop_gained 0.98 0
16:68833419:T Q857* stop_gained 0.98 0
16:68808795:T G212* stop_gained 0.98 0
16:68815519:A L442* stop_gained 0.98 0
16:68823608:T G716* stop_gained 0.98 0
16:68801815:A W103* stop_gained 0.98 0
16:68823435:A L658* stop_gained 0.98 0
16:68823504:A L681* stop_gained 0.98 0
16:68823504:G L681* stop_gained 0.98 0
16:68823435:G L658* stop_gained 0.98 0
16:68815752:T K520* stop_gained 0.98 0
16:68823621:A L720* stop_gained 0.98 0
16:68810341:T G278* stop_gained 0.98 0
16:68808783:T E208* stop_gained 0.98 0
16:68829774:T E806* stop_gained 0.98 0
16:68813401:A W409* stop_gained 0.98 0
16:68813402:A W409* stop_gained 0.98 0
16:68813482:A L436* stop_gained 0.98 0
16:68823417:A L652* stop_gained 0.98 0
16:68808711:T K184* stop_gained 0.98 0
16:68822202:A W638* stop_gained 0.98 0
16:68822203:A W638* stop_gained 0.98 0
16:68822224:C P645P splice_region_variant 0.98 0
16:68822224:G P645P splice_region_variant 0.98 0
16:68822224:T P645P splice_region_variant 0.98 0
16:68823452:T K664* stop_gained 0.98 0
16:68833488:T E880* stop_gained 0.98 0
16:68810270:G D254G missense_variant 0.98 0
16:68811714:G D288G missense_variant 0.98 0
16:68811714:C D288A missense_variant 0.98 0
16:68810270:T D254V missense_variant 0.98 0
16:68810279:T D257V missense_variant 0.98 0
16:68810270:C D254A missense_variant 0.98 0
16:68810279:C D257A missense_variant 0.98 0
16:68833435:A L862* stop_gained 0.98 0
16:68833461:T K871* stop_gained 0.97 0
16:68822018:T G577* stop_gained 0.97 0
16:68810326:T E273* stop_gained 0.97 0
16:68801671:T V55V splice_region_variant 0.97 0
16:68801671:A V55V splice_region_variant 0.97 0
16:68801671:C V55V splice_region_variant 0.97 0
16:68828176:T L723L splice_region_variant 0.97 0
16:68812263:C T379T splice_region_variant 0.97 0
16:68812263:A T379T splice_region_variant 0.97 0
16:68812263:T T379T splice_region_variant 0.97 0
16:68738410:G R54R splice_region_variant 0.96 0
16:68810340:C P277P splice_region_variant 0.96 0
16:68810340:T P277P splice_region_variant 0.96 0
16:68810340:G P277P splice_region_variant 0.96 0
16:68737463:A Q16Q splice_region_variant 0.96 0
16:68829797:G E813E splice_region_variant 0.96 0
16:68808796:C G212A missense_variant 0.96 0
16:68808796:T G212V missense_variant 0.96 0
16:68815683:T E497* stop_gained 0.96 0
16:68815728:T E512* stop_gained 0.96 0
16:68810236:T E243* stop_gained 0.95 0
16:68815638:T E482* stop_gained 0.95 0
16:68811821:T G324* stop_gained 0.95 0
16:68808747:T G196* stop_gained 0.95 0
16:68829699:T E781* stop_gained 0.95 0
16:68833356:T E836* stop_gained 0.95 0
16:68833359:T G837* stop_gained 0.95 0
16:68833444:A W865* stop_gained 0.95 0
16:68828296:T E763* stop_gained 0.95 0
16:68828293:T E762* stop_gained 0.95 0
16:68828290:T G761* stop_gained 0.95 0
16:68833479:T G877* stop_gained 0.95 0
16:68828284:T G759* stop_gained 0.95 0
16:68828278:T E757* stop_gained 0.95 0
16:68833445:A W865* stop_gained 0.95 0
16:68808828:T E223* stop_gained 0.95 0
16:68808695:T I178I splice_region_variant 0.95 0
16:68808695:A I178I splice_region_variant 0.95 0
16:68808503:A W156* stop_gained 0.95 0
16:68808504:A W156* stop_gained 0.95 0
16:68815757:T I521I splice_region_variant 0.94 0
16:68815757:C I521I splice_region_variant 0.94 0
16:68813495:C K440N missense_variant 0.94 0
16:68813475:C G434R missense_variant 0.94 0
16:68813475:A G434S missense_variant 0.94 0
16:68813475:T G434C missense_variant 0.94 0
16:68813379:A D402N missense_variant 0.94 0
16:68813325:C V384L missense_variant 0.94 0
16:68813373:T D400Y missense_variant 0.94 0
16:68813373:C D400H missense_variant 0.94 0
16:68813373:A D400N missense_variant 0.94 0
16:68813331:C E386Q missense_variant 0.94 0
16:68813325:T V384L missense_variant 0.94 0
16:68813331:A E386K missense_variant 0.94 0
16:68813379:T D402Y missense_variant 0.94 0
16:68813325:A V384M missense_variant 0.94 0
16:68810199:G L230L splice_region_variant 0.91 0
16:68810199:T L230L splice_region_variant 0.91 0
16:68810199:A L230L splice_region_variant 0.91 0
16:68819280:G T522T splice_region_variant 0.91 0
16:68819280:C T522T splice_region_variant 0.91 0
16:68819280:T T522T splice_region_variant 0.91 0
16:68833292:C N814N splice_region_variant 0.91 0
16:68822058:T D590V missense_variant 0.91 0
16:68822049:C D587A missense_variant 0.91 0
16:68822055:T N589I missense_variant 0.91 0
16:68822049:G D587G missense_variant 0.91 0
16:68822049:T D587V missense_variant 0.91 0
16:68822054:C N589H missense_variant 0.91 0
16:68822054:G N589D missense_variant 0.91 0
16:68822061:T N591I missense_variant 0.91 0
16:68822061:G N591S missense_variant 0.91 0
16:68822054:T N589Y missense_variant 0.91 0
16:68822061:C N591T missense_variant 0.91 0
16:68822060:T N591Y missense_variant 0.91 0
16:68822060:G N591D missense_variant 0.91 0
16:68822060:C N591H missense_variant 0.91 0
16:68822055:C N589T missense_variant 0.91 0
16:68822055:G N589S missense_variant 0.91 0
16:68822058:G D590G missense_variant 0.91 0
16:68822058:C D590A missense_variant 0.91 0
16:68808567:T Q177H missense_variant 0.90 0
16:68808567:C Q177H missense_variant 0.90 0
16:68823474:C D671A missense_variant 0.89 0
16:68823474:T D671V missense_variant 0.89 0
16:68823474:G D671G missense_variant 0.89 0
16:68815528:G E445G missense_variant 0.89 0
16:68815528:T E445V missense_variant 0.89 0
16:68815522:C D443A missense_variant 0.89 0
16:68815522:G D443G missense_variant 0.89 0
16:68815566:G N458D missense_variant 0.89 0
16:68815567:C N458T missense_variant 0.89 0
16:68815566:T N458Y missense_variant 0.89 0
16:68815528:C E445A missense_variant 0.89 0
16:68815566:C N458H missense_variant 0.89 0
16:68815522:T D443V missense_variant 0.89 0
16:68815608:G T472A missense_variant 0.89 0
16:68815608:C T472P missense_variant 0.89 0
16:68815608:T T472S missense_variant 0.89 0
16:68815567:G N458S missense_variant 0.89 0
16:68811713:T D288Y missense_variant 0.88 0
16:68808795:A G212R missense_variant 0.88 0
16:68811713:C D288H missense_variant 0.88 0
16:68811713:A D288N missense_variant 0.88 0
16:68810269:C D254H missense_variant 0.88 0
16:68810278:C D257H missense_variant 0.88 0
16:68810269:A D254N missense_variant 0.88 0
16:68808795:C G212R missense_variant 0.88 0
16:68810278:T D257Y missense_variant 0.88 0
16:68808826:A R222K missense_variant 0.87 0
16:68808826:C R222T missense_variant 0.87 0
16:68808826:T R222I missense_variant 0.87 0
16:68813332:T E386V missense_variant 0.87 0
16:68813332:G E386G missense_variant 0.87 0
16:68813332:C E386A missense_variant 0.87 0
16:68813374:G D400G missense_variant 0.87 0
16:68813374:C D400A missense_variant 0.87 0
16:68813335:T N387I missense_variant 0.87 0
16:68813380:T D402V missense_variant 0.87 0
16:68813380:G D402G missense_variant 0.87 0
16:68813380:C D402A missense_variant 0.87 0
16:68813335:G N387S missense_variant 0.87 0
16:68813335:C N387T missense_variant 0.87 0
16:68813334:T N387Y missense_variant 0.87 0
16:68813334:G N387D missense_variant 0.87 0
16:68813334:C N387H missense_variant 0.87 0
16:68810207:G H233R missense_variant 0.87 0
16:68810207:T H233L missense_variant 0.87 0
16:68810207:C H233P missense_variant 0.87 0
16:68810327:G E273G missense_variant 0.87 0
16:68810327:C E273A missense_variant 0.87 0
16:68810327:T E273V missense_variant 0.87 0
16:68808829:T E223V missense_variant 0.87 0
16:68808823:T D221V missense_variant 0.87 0
16:68808823:G D221G missense_variant 0.87 0
16:68808823:C D221A missense_variant 0.87 0
16:68808829:C E223A missense_variant 0.87 0
16:68808829:G E223G missense_variant 0.87 0
16:68808822:A D221N missense_variant 0.86 0
16:68811857:C E336Q missense_variant 0.86 0
16:68808822:T D221Y missense_variant 0.86 0
16:68808822:C D221H missense_variant 0.86 0
16:68808533:C N166T missense_variant 0.86 0
16:68808493:C K153Q missense_variant 0.86 0
16:68808494:T K153M missense_variant 0.86 0
16:68808494:G K153R missense_variant 0.86 0
16:68808494:C K153T missense_variant 0.86 0
16:68808533:T N166I missense_variant 0.86 0
16:68808533:G N166S missense_variant 0.86 0
16:68808493:G K153E missense_variant 0.86 0
16:68808532:T N166Y missense_variant 0.86 0
16:68808532:G N166D missense_variant 0.86 0
16:68808532:C N166H missense_variant 0.86 0
16:68808530:T E165V missense_variant 0.86 0
16:68808530:G E165G missense_variant 0.86 0
16:68808530:C E165A missense_variant 0.86 0
16:68815515:A G441S missense_variant 0.86 0
16:68815515:C G441R missense_variant 0.86 0
16:68815515:T G441C missense_variant 0.86 0
16:68829783:C N809H missense_variant 0.86 0
16:68829783:G N809D missense_variant 0.86 0
16:68829783:T N809Y missense_variant 0.86 0
16:68812172:T D349V missense_variant 0.86 0
16:68812172:C D349A missense_variant 0.86 0
16:68812148:T Y341F missense_variant 0.86 0
16:68812148:G Y341C missense_variant 0.86 0
16:68812148:C Y341S missense_variant 0.86 0
16:68812238:C N371T missense_variant 0.86 0
16:68812238:G N371S missense_variant 0.86 0
16:68812238:T N371I missense_variant 0.86 0
16:68812172:G D349G missense_variant 0.86 0
16:68812235:C D370A missense_variant 0.86 0
16:68812235:G D370G missense_variant 0.86 0
16:68812232:G N369S missense_variant 0.86 0
16:68812235:T D370V missense_variant 0.86 0
16:68812232:C N369T missense_variant 0.86 0
16:68812232:T N369I missense_variant 0.86 0
16:68828281:C E758Q missense_variant 0.85 0
16:68828281:A E758K missense_variant 0.85 0
16:68833390:A S847Y missense_variant 0.85 0
16:68833390:G S847C missense_variant 0.85 0
16:68833390:T S847F missense_variant 0.85 0
16:68811799:C M316I missense_variant 0.85 0
16:68811799:T M316I missense_variant 0.85 0
16:68811799:A M316I missense_variant 0.85 0
16:68813454:T T427S missense_variant 0.85 0
16:68813454:G T427A missense_variant 0.85 0
16:68813454:C T427P missense_variant 0.85 0
16:68829787:C F810S missense_variant 0.85 0
16:68829787:G F810C missense_variant 0.85 0
16:68829790:A I811N missense_variant 0.85 0
16:68829790:C I811T missense_variant 0.85 0
16:68829790:G I811S missense_variant 0.85 0
16:68829786:C F810L missense_variant 0.85 0
16:68829786:G F810V missense_variant 0.85 0
16:68829787:A F810Y missense_variant 0.85 0
16:68829786:A F810I missense_variant 0.85 0
16:68810247:A M246I missense_variant 0.85 0
16:68810247:C M246I missense_variant 0.85 0
16:68810247:T M246I missense_variant 0.85 0
16:68808781:G I207S missense_variant 0.85 0
16:68808694:A I178N missense_variant 0.85 0
16:68808694:C I178T missense_variant 0.85 0
16:68808694:G I178S missense_variant 0.85 0
16:68808724:C V188A missense_variant 0.85 0
16:68808724:G V188G missense_variant 0.85 0
16:68808729:A Y190N missense_variant 0.85 0
16:68808729:C Y190H missense_variant 0.85 0
16:68808729:G Y190D missense_variant 0.85 0
16:68808736:C I192T missense_variant 0.85 0
16:68808736:G I192S missense_variant 0.85 0
16:68808774:A F205I missense_variant 0.85 0
16:68808774:C F205L missense_variant 0.85 0
16:68808774:G F205V missense_variant 0.85 0
16:68808775:A F205Y missense_variant 0.85 0
16:68808775:C F205S missense_variant 0.85 0
16:68808775:G F205C missense_variant 0.85 0
16:68808781:A I207N missense_variant 0.85 0
16:68808781:C I207T missense_variant 0.85 0
16:68808802:A L214Q missense_variant 0.85 0
16:68808802:C L214P missense_variant 0.85 0
16:68808802:G L214R missense_variant 0.85 0
16:68808808:A V216E missense_variant 0.85 0
16:68808808:C V216A missense_variant 0.85 0
16:68808808:G V216G missense_variant 0.85 0
16:68810252:A I248N missense_variant 0.85 0
16:68810252:C I248T missense_variant 0.85 0
16:68810252:G I248S missense_variant 0.85 0
16:68810258:A I250N missense_variant 0.85 0
16:68810258:C I250T missense_variant 0.85 0
16:68810258:G I250S missense_variant 0.85 0
16:68810264:A V252E missense_variant 0.85 0
16:68810264:C V252A missense_variant 0.85 0
16:68810264:G V252G missense_variant 0.85 0
16:68811693:A V281E missense_variant 0.85 0
16:68811693:C V281A missense_variant 0.85 0
16:68811693:G V281G missense_variant 0.85 0
16:68811696:A M282K missense_variant 0.85 0
16:68811696:C M282T missense_variant 0.85 0
16:68811696:G M282R missense_variant 0.85 0
16:68811702:A V284D missense_variant 0.85 0
16:68811702:C V284A missense_variant 0.85 0
16:68811702:G V284G missense_variant 0.85 0
16:68811755:A Y302N missense_variant 0.85 0
16:68811755:C Y302H missense_variant 0.85 0
16:68811755:G Y302D missense_variant 0.85 0
16:68811762:A I304N missense_variant 0.85 0
16:68811762:C I304T missense_variant 0.85 0
16:68811762:G I304S missense_variant 0.85 0
16:68811798:A M316K missense_variant 0.85 0
16:68811798:C M316T missense_variant 0.85 0
16:68811798:G M316R missense_variant 0.85 0
16:68811800:A F317I missense_variant 0.85 0
16:68811800:C F317L missense_variant 0.85 0
16:68811800:G F317V missense_variant 0.85 0
16:68811801:A F317Y missense_variant 0.85 0
16:68811801:G F317C missense_variant 0.85 0
16:68811807:A I319N missense_variant 0.85 0
16:68811807:C I319T missense_variant 0.85 0
16:68811807:G I319S missense_variant 0.85 0
16:68811828:A I326N missense_variant 0.85 0
16:68811828:C I326T missense_variant 0.85 0
16:68811828:G I326S missense_variant 0.85 0
16:68811846:A G332E missense_variant 0.85 0
16:68811846:C G332A missense_variant 0.85 0
16:68811846:T G332V missense_variant 0.85 0
16:68811849:A L333Q missense_variant 0.85 0
16:68811849:C L333P missense_variant 0.85 0
16:68811849:G L333R missense_variant 0.85 0
16:68815624:A V477E missense_variant 0.85 0
16:68815624:C V477A missense_variant 0.85 0
16:68815624:G V477G missense_variant 0.85 0
16:68815650:A F486I missense_variant 0.85 0
16:68815650:C F486L missense_variant 0.85 0
16:68815650:G F486V missense_variant 0.85 0
16:68815651:A F486Y missense_variant 0.85 0
16:68815651:C F486S missense_variant 0.85 0
16:68815651:G F486C missense_variant 0.85 0
16:68811707:C A286P missense_variant 0.85 0
16:68811707:A A286T missense_variant 0.85 0
16:68811707:T A286S missense_variant 0.85 0
16:68815527:A E445K missense_variant 0.84 0
16:68815527:C E445Q missense_variant 0.84 0
16:68815521:A D443N missense_variant 0.84 0
16:68815521:C D443H missense_variant 0.84 0
16:68815521:T D443Y missense_variant 0.84 0
16:68808750:C A197P missense_variant 0.84 0
16:68808750:T A197S missense_variant 0.84 0
16:68808750:A A197T missense_variant 0.84 0
16:68808542:A G169D missense_variant 0.84 0
16:68808542:T G169V missense_variant 0.84 0
16:68808542:C G169A missense_variant 0.84 0
16:68822021:G T578A missense_variant 0.84 0
16:68822021:T T578S missense_variant 0.84 0
16:68822027:C T580P missense_variant 0.84 0
16:68822027:G T580A missense_variant 0.84 0
16:68822027:T T580S missense_variant 0.84 0
16:68822015:T T576S missense_variant 0.84 0
16:68822015:G T576A missense_variant 0.84 0
16:68822015:C T576P missense_variant 0.84 0
16:68822021:C T578P missense_variant 0.84 0
16:68829769:A P804H missense_variant 0.84 0
16:68829723:A P789T missense_variant 0.84 0
16:68829723:G P789A missense_variant 0.84 0
16:68829723:T P789S missense_variant 0.84 0
16:68829724:A P789Q missense_variant 0.84 0
16:68829724:G P789R missense_variant 0.84 0
16:68829724:T P789L missense_variant 0.84 0
16:68829768:A P804T missense_variant 0.84 0
16:68829768:G P804A missense_variant 0.84 0
16:68829768:T P804S missense_variant 0.84 0
16:68829769:G P804R missense_variant 0.84 0
16:68829769:T P804L missense_variant 0.84 0
16:68829697:A P780H missense_variant 0.84 0
16:68829696:G P780A missense_variant 0.84 0
16:68829696:A P780T missense_variant 0.84 0
16:68829697:T P780L missense_variant 0.84 0
16:68829697:G P780R missense_variant 0.84 0
16:68829696:T P780S missense_variant 0.84 0
16:68829675:A H773N missense_variant 0.83 0
16:68829675:T H773Y missense_variant 0.83 0
16:68829675:G H773D missense_variant 0.83 0
16:68828302:A Q765K missense_variant 0.83 0
16:68828302:G Q765E missense_variant 0.83 0
16:68833327:G P826R missense_variant 0.83 0
16:68833327:T P826L missense_variant 0.83 0
16:68833323:T P825S missense_variant 0.83 0
16:68833323:G P825A missense_variant 0.83 0
16:68833323:A P825T missense_variant 0.83 0
16:68833314:T P822S missense_variant 0.83 0
16:68833324:T P825L missense_variant 0.83 0
16:68833314:G P822A missense_variant 0.83 0
16:68833314:A P822T missense_variant 0.83 0
16:68833303:A A818D missense_variant 0.83 0
16:68833324:G P825R missense_variant 0.83 0
16:68829747:G Y797D missense_variant 0.83 0
16:68829747:C Y797H missense_variant 0.83 0
16:68829747:A Y797N missense_variant 0.83 0
16:68833300:T A817V missense_variant 0.83 0
16:68833300:A A817E missense_variant 0.83 0
16:68833326:G P826A missense_variant 0.83 0
16:68833326:A P826T missense_variant 0.83 0
16:68833468:T A873V missense_variant 0.83 0
16:68833468:G A873G missense_variant 0.83 0
16:68833468:A A873D missense_variant 0.83 0
16:68833399:T S850F missense_variant 0.83 0
16:68833419:A Q857K missense_variant 0.83 0
16:68833419:G Q857E missense_variant 0.83 0
16:68833369:A S840Y missense_variant 0.83 0
16:68833369:G S840C missense_variant 0.83 0
16:68833369:T S840F missense_variant 0.83 0
16:68833399:A S850Y missense_variant 0.83 0
16:68833399:G S850C missense_variant 0.83 0
16:68833324:A P825Q missense_variant 0.83 0
16:68833300:G A817G missense_variant 0.83 0
16:68833303:G A818G missense_variant 0.83 0
16:68833303:T A818V missense_variant 0.83 0
16:68833327:A P826H missense_variant 0.83 0
16:68833326:T P826S missense_variant 0.83 0
16:68819420:T D569V missense_variant 0.81 0
16:68819420:G D569G missense_variant 0.81 0
16:68819420:C D569A missense_variant 0.81 0
16:68819396:T Y561F missense_variant 0.81 0
16:68819387:C N558T missense_variant 0.81 0
16:68819387:T N558I missense_variant 0.81 0
16:68819387:G N558S missense_variant 0.81 0
16:68819396:C Y561S missense_variant 0.81 0
16:68819396:G Y561C missense_variant 0.81 0
16:68829682:C G775A missense_variant 0.81 0
16:68829703:G V782G missense_variant 0.81 0
16:68829703:C V782A missense_variant 0.81 0
16:68829703:A V782E missense_variant 0.81 0
16:68829682:A G775D missense_variant 0.81 0
16:68829682:T G775V missense_variant 0.81 0
16:68819332:T G540C missense_variant 0.80 0
16:68819359:T D549Y missense_variant 0.80 0
16:68819359:C D549H missense_variant 0.80 0
16:68819359:A D549N missense_variant 0.80 0
16:68819332:C G540R missense_variant 0.80 0
16:68819332:A G540S missense_variant 0.80 0
16:68819310:T W532C missense_variant 0.80 0
16:68819310:C W532C missense_variant 0.80 0
16:68819309:T W532L missense_variant 0.80 0
16:68819309:C W532S missense_variant 0.80 0
16:68811756:T Y302F missense_variant 0.80 0
16:68808730:C Y190S missense_variant 0.80 0
16:68808730:T Y190F missense_variant 0.80 0
16:68808732:C S191R missense_variant 0.80 0
16:68808732:G S191G missense_variant 0.80 0
16:68808732:T S191C missense_variant 0.80 0
16:68811858:T E336V missense_variant 0.80 0
16:68811858:G E336G missense_variant 0.80 0
16:68815630:C D479A missense_variant 0.80 0
16:68810237:C E243A missense_variant 0.80 0
16:68811858:C E336A missense_variant 0.80 0
16:68811852:T D334V missense_variant 0.80 0
16:68811852:G D334G missense_variant 0.80 0
16:68810237:G E243G missense_variant 0.80 0
16:68810237:T E243V missense_variant 0.80 0
16:68811852:C D334A missense_variant 0.80 0
16:68811810:T N320I missense_variant 0.80 0
16:68811810:G N320S missense_variant 0.80 0
16:68815630:G D479G missense_variant 0.80 0
16:68815630:T D479V missense_variant 0.80 0
16:68811810:C N320T missense_variant 0.80 0
16:68815635:C N481H missense_variant 0.80 0
16:68810275:C N256H missense_variant 0.80 0
16:68810275:G N256D missense_variant 0.80 0
16:68810275:T N256Y missense_variant 0.80 0
16:68810276:C N256T missense_variant 0.80 0
16:68815635:G N481D missense_variant 0.80 0
16:68815635:T N481Y missense_variant 0.80 0
16:68815636:C N481T missense_variant 0.80 0
16:68811771:T Q307L missense_variant 0.80 0
16:68815636:G N481S missense_variant 0.80 0
16:68815636:T N481I missense_variant 0.80 0
16:68811771:G Q307R missense_variant 0.80 0
16:68810276:G N256S missense_variant 0.80 0
16:68810276:T N256I missense_variant 0.80 0
16:68810281:C N258H missense_variant 0.80 0
16:68815639:C E482A missense_variant 0.80 0
16:68810281:G N258D missense_variant 0.80 0
16:68811771:C Q307P missense_variant 0.80 0
16:68811761:T I304F missense_variant 0.80 0
16:68815639:G E482G missense_variant 0.80 0
16:68815639:T E482V missense_variant 0.80 0
16:68811761:G I304V missense_variant 0.80 0
16:68811761:C I304L missense_variant 0.80 0
16:68811756:G Y302C missense_variant 0.80 0
16:68811756:C Y302S missense_variant 0.80 0
16:68811740:T N297Y missense_variant 0.80 0
16:68811740:G N297D missense_variant 0.80 0
16:68811740:C N297H missense_variant 0.80 0
16:68811723:T D291V missense_variant 0.80 0
16:68811723:G D291G missense_variant 0.80 0
16:68811723:C D291A missense_variant 0.80 0
16:68810281:T N258Y missense_variant 0.80 0
16:68810282:C N258T missense_variant 0.80 0
16:68810282:T N258I missense_variant 0.80 0
16:68810282:G N258S missense_variant 0.80 0
16:68823605:C G715R missense_variant 0.80 0
16:68823605:A G715R missense_variant 0.80 0
16:68828275:T D756Y missense_variant 0.79 0
16:68828275:C D756H missense_variant 0.79 0
16:68828275:A D756N missense_variant 0.79 0
16:68822199:C N637T missense_variant 0.78 0
16:68822198:T N637Y missense_variant 0.78 0
16:68822199:T N637I missense_variant 0.78 0
16:68822198:G N637D missense_variant 0.78 0
16:68822198:C N637H missense_variant 0.78 0
16:68822199:G N637S missense_variant 0.78 0
16:68815698:C G502R missense_variant 0.78 0
16:68815698:A G502S missense_variant 0.78 0
16:68815698:T G502C missense_variant 0.78 0
16:68829681:C G775R missense_variant 0.77 0
16:68813494:C K440T missense_variant 0.77 0
16:68813494:G K440R missense_variant 0.77 0
16:68813494:T K440M missense_variant 0.77 0
16:68829681:T G775C missense_variant 0.77 0
16:68829681:A G775S missense_variant 0.77 0
16:68819413:A A567T missense_variant 0.76 0
16:68819419:T D569Y missense_variant 0.76 0
16:68819419:C D569H missense_variant 0.76 0
16:68819425:A G571S missense_variant 0.76 0
16:68819425:T G571C missense_variant 0.76 0
16:68819419:A D569N missense_variant 0.76 0
16:68819425:C G571R missense_variant 0.76 0
16:68819413:C A567P missense_variant 0.76 0
16:68819413:T A567S missense_variant 0.76 0
16:68815708:G I505S missense_variant 0.76 0
16:68815756:A I521K missense_variant 0.76 0
16:68815756:C I521T missense_variant 0.76 0
16:68815756:G I521R missense_variant 0.76 0
16:68815708:A I505N missense_variant 0.76 0
16:68815708:C I505T missense_variant 0.76 0
16:68823531:T G690V missense_variant 0.75 0
16:68823531:A G690E missense_variant 0.75 0
16:68823531:C G690A missense_variant 0.75 0
16:68810248:A E247K missense_variant 0.74 0
16:68828195:C L729P missense_variant 0.74 0
16:68828195:A L729Q missense_variant 0.74 0
16:68808529:A E165K missense_variant 0.74 0
16:68828195:G L729R missense_variant 0.74 0
16:68808529:C E165Q missense_variant 0.74 0
16:68828192:G L728W missense_variant 0.74 0
16:68828192:C L728S missense_variant 0.74 0
16:68810248:C E247Q missense_variant 0.74 0
16:68812187:A G354E missense_variant 0.74 0
16:68812187:T G354V missense_variant 0.74 0
16:68812187:C G354A missense_variant 0.74 0
16:68808820:A L220Q missense_variant 0.71 0
16:68808820:C L220P missense_variant 0.71 0
16:68808820:G L220R missense_variant 0.71 0
16:68815735:T D514V missense_variant 0.70 0
16:68815729:C E512A missense_variant 0.70 0
16:68815684:G E497G missense_variant 0.70 0
16:68815735:C D514A missense_variant 0.70 0
16:68815684:T E497V missense_variant 0.70 0
16:68815735:G D514G missense_variant 0.70 0
16:68815750:C Q519P missense_variant 0.70 0
16:68815750:T Q519L missense_variant 0.70 0
16:68815750:G Q519R missense_variant 0.70 0
16:68815752:C K520Q missense_variant 0.70 0
16:68815684:C E497A missense_variant 0.70 0
16:68815729:T E512V missense_variant 0.70 0
16:68815729:G E512G missense_variant 0.70 0
16:68815752:G K520E missense_variant 0.70 0
16:68833488:A E880K missense_variant 0.70 0
16:68833305:C D819H missense_variant 0.70 0
16:68833305:A D819N missense_variant 0.70 0
16:68833344:A V832M missense_variant 0.70 0
16:68833488:C E880Q missense_variant 0.70 0
16:68833344:T V832L missense_variant 0.70 0
16:68833344:C V832L missense_variant 0.70 0
16:68833305:T D819Y missense_variant 0.70 0
16:68833365:C G839R missense_variant 0.69 0
16:68833365:A G839S missense_variant 0.69 0
16:68833365:T G839C missense_variant 0.69 0
16:68815612:A V473D missense_variant 0.69 0
16:68815524:G F444V missense_variant 0.69 0
16:68815524:C F444L missense_variant 0.69 0
16:68828177:A L723Q missense_variant 0.69 0
16:68828177:C L723P missense_variant 0.69 0
16:68828177:G L723R missense_variant 0.69 0
16:68815524:A F444I missense_variant 0.69 0
16:68815555:C V454A missense_variant 0.69 0
16:68815519:C L442S missense_variant 0.69 0
16:68815618:C V475A missense_variant 0.69 0
16:68815612:C V473A missense_variant 0.69 0
16:68815612:G V473G missense_variant 0.69 0
16:68815618:A V475E missense_variant 0.69 0
16:68815618:G V475G missense_variant 0.69 0
16:68815519:G L442W missense_variant 0.69 0
16:68815555:G V454G missense_variant 0.69 0
16:68833474:G M875R missense_variant 0.67 0
16:68833348:C F833S missense_variant 0.67 0
16:68833348:A F833Y missense_variant 0.67 0
16:68833347:G F833V missense_variant 0.67 0
16:68833347:C F833L missense_variant 0.67 0
16:68833294:A L815Q missense_variant 0.67 0
16:68833294:C L815P missense_variant 0.67 0
16:68833294:G L815R missense_variant 0.67 0
16:68833329:A Y827N missense_variant 0.67 0
16:68833329:C Y827H missense_variant 0.67 0
16:68833329:G Y827D missense_variant 0.67 0
16:68833465:A L872Q missense_variant 0.67 0
16:68833465:C L872P missense_variant 0.67 0
16:68833465:G L872R missense_variant 0.67 0
16:68833347:A F833I missense_variant 0.67 0
16:68833345:G V832G missense_variant 0.67 0
16:68833345:C V832A missense_variant 0.67 0
16:68833342:A L831H missense_variant 0.67 0
16:68833342:C L831P missense_variant 0.67 0
16:68833342:G L831R missense_variant 0.67 0
16:68833345:A V832E missense_variant 0.67 0
16:68833474:A M875K missense_variant 0.67 0
16:68833456:G F869C missense_variant 0.67 0
16:68833456:C F869S missense_variant 0.67 0
16:68833456:A F869Y missense_variant 0.67 0
16:68833455:G F869V missense_variant 0.67 0
16:68833455:C F869L missense_variant 0.67 0
16:68833455:A F869I missense_variant 0.67 0
16:68833425:G Y859D missense_variant 0.67 0
16:68833425:C Y859H missense_variant 0.67 0
16:68833425:A Y859N missense_variant 0.67 0
16:68833476:G Y876D missense_variant 0.67 0
16:68833476:C Y876H missense_variant 0.67 0
16:68833476:A Y876N missense_variant 0.67 0
16:68833474:C M875T missense_variant 0.67 0
16:68833348:G F833C missense_variant 0.67 0
16:68829685:C L776P missense_variant 0.67 0
16:68829657:A F767I missense_variant 0.67 0
16:68829657:C F767L missense_variant 0.67 0
16:68829657:G F767V missense_variant 0.67 0
16:68829673:A L772Q missense_variant 0.67 0
16:68829673:C L772P missense_variant 0.67 0
16:68829673:G L772R missense_variant 0.67 0
16:68829685:A L776Q missense_variant 0.67 0
16:68829685:G L776R missense_variant 0.67 0
16:68833435:C L862S missense_variant 0.67 0
16:68833435:G L862W missense_variant 0.67 0
16:68828245:C D746H missense_variant 0.67 0
16:68828245:T D746Y missense_variant 0.67 0
16:68828245:A D746N missense_variant 0.67 0
16:68833491:C D881H missense_variant 0.67 0
16:68833491:A D881N missense_variant 0.67 0
16:68833491:T D881Y missense_variant 0.67 0
16:68828264:G V752G missense_variant 0.67 0
16:68828264:C V752A missense_variant 0.67 0
16:68829667:T S770I missense_variant 0.67 0
16:68828264:A V752D missense_variant 0.67 0
16:68829667:C S770T missense_variant 0.67 0
16:68829667:A S770N missense_variant 0.67 0
16:68828272:G Y755D missense_variant 0.67 0
16:68828272:A Y755N missense_variant 0.67 0
16:68828272:C Y755H missense_variant 0.67 0
16:68829694:C R779P missense_variant 0.67 0
16:68833368:G S840A missense_variant 0.67 0
16:68833368:C S840P missense_variant 0.67 0
16:68833368:A S840T missense_variant 0.67 0
16:68829694:A R779Q missense_variant 0.67 0
16:68829694:T R779L missense_variant 0.67 0
16:68833374:T A842S missense_variant 0.67 0
16:68833374:A A842T missense_variant 0.67 0
16:68833374:C A842P missense_variant 0.67 0
16:68833483:A G878D missense_variant 0.66 0
16:68833483:C G878A missense_variant 0.66 0
16:68833483:T G878V missense_variant 0.66 0
16:68833416:C D856H missense_variant 0.66 0
16:68833416:A D856N missense_variant 0.66 0
16:68833416:T D856Y missense_variant 0.66 0
16:68828304:T Q765H missense_variant 0.66 0
16:68828304:C Q765H missense_variant 0.66 0
16:68823444:A G661D missense_variant 0.64 0
16:68823443:T G661C missense_variant 0.64 0
16:68823443:C G661R missense_variant 0.64 0
16:68823443:A G661S missense_variant 0.64 0
16:68823444:T G661V missense_variant 0.64 0
16:68823444:C G661A missense_variant 0.64 0
16:68828261:G N751S missense_variant 0.59 0
16:68828273:T Y755F missense_variant 0.59 0
16:68828273:G Y755C missense_variant 0.59 0
16:68828261:T N751I missense_variant 0.59 0
16:68828258:C D750A missense_variant 0.59 0
16:68828258:G D750G missense_variant 0.59 0
16:68828258:T D750V missense_variant 0.59 0
16:68828243:C E745A missense_variant 0.59 0
16:68828243:G E745G missense_variant 0.59 0
16:68828243:T E745V missense_variant 0.59 0
16:68828273:C Y755S missense_variant 0.59 0
16:68828261:C N751T missense_variant 0.59 0
16:68829661:C D768A missense_variant 0.57 0
16:68829655:G D766G missense_variant 0.57 0
16:68829655:T D766V missense_variant 0.57 0
16:68829655:C D766A missense_variant 0.57 0
16:68829661:G D768G missense_variant 0.57 0
16:68829661:T D768V missense_variant 0.57 0
16:68819282:T Y523F missense_variant 0.56 0
16:68819282:G Y523C missense_variant 0.56 0
16:68819282:C Y523S missense_variant 0.56 0
16:68833461:C K871Q missense_variant 0.55 0
16:68833312:G D821G missense_variant 0.55 0
16:68833312:C D821A missense_variant 0.55 0
16:68833306:T D819V missense_variant 0.55 0
16:68833306:G D819G missense_variant 0.55 0
16:68833306:C D819A missense_variant 0.55 0
16:68833333:C D828A missense_variant 0.55 0
16:68833333:G D828G missense_variant 0.55 0
16:68833333:T D828V missense_variant 0.55 0
16:68833351:C D834A missense_variant 0.55 0
16:68833351:G D834G missense_variant 0.55 0
16:68833351:T D834V missense_variant 0.55 0
16:68833357:C E836A missense_variant 0.55 0
16:68833357:G E836G missense_variant 0.55 0
16:68833357:T E836V missense_variant 0.55 0
16:68833417:C D856A missense_variant 0.55 0
16:68833417:G D856G missense_variant 0.55 0
16:68833417:T D856V missense_variant 0.55 0
16:68833420:C Q857P missense_variant 0.55 0
16:68833420:G Q857R missense_variant 0.55 0
16:68833420:T Q857L missense_variant 0.55 0
16:68833312:T D821V missense_variant 0.55 0
16:68833461:G K871E missense_variant 0.55 0
16:68833471:C D874A missense_variant 0.55 0
16:68833471:G D874G missense_variant 0.55 0
16:68833471:T D874V missense_variant 0.55 0
16:68833477:C Y876S missense_variant 0.55 0
16:68833477:G Y876C missense_variant 0.55 0
16:68833477:T Y876F missense_variant 0.55 0
16:68833395:C N849H missense_variant 0.55 0
16:68833395:T N849Y missense_variant 0.55 0
16:68833395:G N849D missense_variant 0.55 0
16:68829789:T I811F missense_variant 0.54 0
16:68829796:G E813G missense_variant 0.54 0
16:68829796:T E813V missense_variant 0.54 0
16:68829796:C E813A missense_variant 0.54 0
16:68829789:C I811L missense_variant 0.54 0
16:68829789:G I811V missense_variant 0.54 0
16:68829715:G D786G missense_variant 0.54 0
16:68829715:T D786V missense_variant 0.54 0
16:68829715:C D786A missense_variant 0.54 0
16:68822048:T D587Y missense_variant 0.54 0
16:68822048:A D587N missense_variant 0.54 0
16:68822057:C D590H missense_variant 0.54 0
16:68822057:T D590Y missense_variant 0.54 0
16:68822063:T A592S missense_variant 0.54 0
16:68822063:C A592P missense_variant 0.54 0
16:68822063:A A592T missense_variant 0.54 0
16:68822057:A D590N missense_variant 0.54 0
16:68822048:C D587H missense_variant 0.54 0
16:68828294:G E762G missense_variant 0.53 0
16:68828297:C E763A missense_variant 0.53 0
16:68828297:G E763G missense_variant 0.53 0
16:68828297:T E763V missense_variant 0.53 0
16:68828300:C D764A missense_variant 0.53 0
16:68828300:G D764G missense_variant 0.53 0
16:68828300:T D764V missense_variant 0.53 0
16:68828303:C Q765P missense_variant 0.53 0
16:68828303:G Q765R missense_variant 0.53 0
16:68828303:T Q765L missense_variant 0.53 0
16:68828282:C E758A missense_variant 0.53 0
16:68828282:G E758G missense_variant 0.53 0
16:68828282:T E758V missense_variant 0.53 0
16:68828294:C E762A missense_variant 0.53 0
16:68828294:T E762V missense_variant 0.53 0
16:68828279:C E757A missense_variant 0.53 0
16:68828279:G E757G missense_variant 0.53 0
16:68828279:T E757V missense_variant 0.53 0
16:68810314:A G269R missense_variant 0.50 0
16:68810326:A E273K missense_variant 0.50 0
16:68810326:C E273Q missense_variant 0.50 0
16:68810314:C G269R missense_variant 0.50 0
16:68810314:T G269W missense_variant 0.50 0
In silico saturation mutagenesis
Alt text Show figure caption
Cancer type Selected cancer type Mutational discovery Index Feature Complexity
(ST) Stomach adenocarcinoma SOLID 0.22 0.12