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Note: You're navigating the results of models obtained with the previous release of IntOGen (2020). A new boostDM version corresponding to the current IntOGen release will be available soon.
AMER1 COREAD ×
Select a mutation to see further information
Mutation AA change Consequence type BoostDM score IntOGen frequency
X:64191798:A R497* stop_gained 1.00 9
X:64192215:A R358* stop_gained 1.00 8
X:64191411:A R626* stop_gained 1.00 8
X:64191531:A R586* stop_gained 1.00 6
X:64192230:A R353* stop_gained 1.00 5
X:64191696:A R531* stop_gained 1.00 4
X:64191396:A R631* stop_gained 1.00 4
X:64191486:A R601* stop_gained 1.00 4
X:64191903:A E462* stop_gained 1.00 2
X:64191849:A E480* stop_gained 1.00 2
X:64191552:A E579* stop_gained 1.00 1
X:64191874:C Y471* stop_gained 1.00 1
X:64191498:A E597* stop_gained 1.00 1
X:64191423:A E622* stop_gained 1.00 1
X:64192116:A E391* stop_gained 1.00 1
X:64191366:A R641* stop_gained 1.00 1
X:64192149:A E380* stop_gained 1.00 1
X:64192057:T W410* stop_gained 1.00 1
X:64191588:A Q567* stop_gained 1.00 1
X:64192179:A E370* stop_gained 1.00 1
X:64192492:T C265* stop_gained 1.00 0
X:64192593:A Q232* stop_gained 1.00 0
X:64192113:A E392* stop_gained 1.00 0
X:64193175:A E38* stop_gained 1.00 0
X:64190163:A Q1042* stop_gained 1.00 0
X:64190413:T W958* stop_gained 1.00 0
X:64192134:A E385* stop_gained 1.00 0
X:64190270:C S1006* stop_gained 1.00 0
X:64190270:T S1006* stop_gained 1.00 0
X:64192118:C L390* stop_gained 1.00 0
X:64192118:T L390* stop_gained 1.00 0
X:64190232:A Q1019* stop_gained 1.00 0
X:64193193:A K32* stop_gained 1.00 0
X:64190365:T W974* stop_gained 1.00 0
X:64191213:A E692* stop_gained 1.00 0
X:64190467:T W940* stop_gained 1.00 0
X:64191513:A E592* stop_gained 1.00 0
X:64190725:C Y854* stop_gained 1.00 0
X:64191741:A E516* stop_gained 1.00 0
X:64190725:T Y854* stop_gained 1.00 0
X:64192012:C Y425* stop_gained 1.00 0
X:64192012:T Y425* stop_gained 1.00 0
X:64192092:A E399* stop_gained 1.00 0
X:64191715:T C524* stop_gained 1.00 0
X:64191408:A E627* stop_gained 1.00 0
X:64191136:T C717* stop_gained 1.00 0
X:64191043:T Y748* stop_gained 1.00 0
X:64191043:C Y748* stop_gained 1.00 0
X:64190262:A E1009* stop_gained 1.00 0
X:64190710:C Y859* stop_gained 1.00 0
X:64190710:T Y859* stop_gained 1.00 0
X:64193086:T C67* stop_gained 1.00 0
X:64193253:A K12* stop_gained 1.00 0
X:64193277:A Q4* stop_gained 1.00 0
X:64190496:A E931* stop_gained 1.00 0
X:64190671:T Y872* stop_gained 1.00 0
X:64190671:C Y872* stop_gained 1.00 0
X:64193220:A Q23* stop_gained 1.00 0
X:64192686:A R201* stop_gained 1.00 0
X:64190475:A G938* stop_gained 1.00 0
X:64190463:A R942* stop_gained 1.00 0
X:64190514:A Q925* stop_gained 1.00 0
X:64191874:T Y471* stop_gained 1.00 0
X:64191348:A Q647* stop_gained 1.00 0
X:64189915:T Y1124* stop_gained 1.00 0
X:64189915:C Y1124* stop_gained 1.00 0
X:64191172:T Y705* stop_gained 1.00 0
X:64191172:C Y705* stop_gained 1.00 0
X:64190094:A G1065* stop_gained 1.00 0
X:64191979:C Y436* stop_gained 1.00 0
X:64191979:T Y436* stop_gained 1.00 0
X:64190646:A R881* stop_gained 1.00 0
X:64192635:A E218* stop_gained 1.00 0
X:64192101:A E396* stop_gained 1.00 0
X:64189884:A K1135* stop_gained 1.00 0
X:64190188:T C1033* stop_gained 1.00 0
X:64190923:T C788* stop_gained 1.00 0
X:64190542:T Y915* stop_gained 1.00 0
X:64190542:C Y915* stop_gained 1.00 0
X:64192521:A K256* stop_gained 1.00 0
X:64192536:A E251* stop_gained 1.00 0
X:64192056:A E411* stop_gained 1.00 0
X:64189981:C Y1102* stop_gained 1.00 0
X:64189981:T Y1102* stop_gained 1.00 0
X:64192639:T C216* stop_gained 1.00 0
X:64192413:A K292* stop_gained 1.00 0
X:64192095:A K398* stop_gained 1.00 0
X:64191357:A Q644* stop_gained 1.00 0
X:64191382:T C635* stop_gained 1.00 0
X:64190107:T C1060* stop_gained 1.00 0
X:64190440:C Y949* stop_gained 1.00 0
X:64190440:T Y949* stop_gained 1.00 0
X:64189944:A E1115* stop_gained 1.00 0
X:64191475:T Y604* stop_gained 1.00 0
X:64191475:C Y604* stop_gained 1.00 0
X:64191460:T Y609* stop_gained 1.00 0
X:64191460:C Y609* stop_gained 1.00 0
X:64191440:T W616* stop_gained 1.00 0
X:64191439:T W616* stop_gained 1.00 0
X:64191417:A R624* stop_gained 1.00 0
X:64190419:T Y956* stop_gained 1.00 0
X:64190419:C Y956* stop_gained 1.00 0
X:64190302:T C995* stop_gained 1.00 0
X:64191402:A Q629* stop_gained 1.00 0
X:64190244:A E1015* stop_gained 1.00 0
X:64191381:A R636* stop_gained 1.00 0
X:64192509:A K260* stop_gained 1.00 0
X:64193250:A G13* stop_gained 1.00 0
X:64191805:T C494* stop_gained 1.00 0
X:64192522:T C255* stop_gained 1.00 0
X:64192458:A E277* stop_gained 1.00 0
X:64191952:C Y445* stop_gained 1.00 0
X:64191952:T Y445* stop_gained 1.00 0
X:64192858:T C143* stop_gained 1.00 0
X:64190749:C Y846* stop_gained 1.00 0
X:64190749:T Y846* stop_gained 1.00 0
X:64192611:A K226* stop_gained 1.00 0
X:64193150:C S46* stop_gained 1.00 0
X:64193150:T S46* stop_gained 1.00 0
X:64193223:A E22* stop_gained 1.00 0
X:64191577:T Y570* stop_gained 1.00 0
X:64191577:C Y570* stop_gained 1.00 0
X:64190305:T C994* stop_gained 1.00 0
X:64192401:A G296* stop_gained 1.00 0
X:64192303:T C328* stop_gained 1.00 0
X:64191490:C Y599* stop_gained 1.00 0
X:64191490:T Y599* stop_gained 1.00 0
X:64190414:T W958* stop_gained 1.00 0
X:64190490:A E933* stop_gained 1.00 0
X:64192039:T Y416* stop_gained 1.00 0
X:64192039:C Y416* stop_gained 1.00 0
X:64193205:A G28* stop_gained 1.00 0
X:64192416:A E291* stop_gained 1.00 0
X:64190821:T C822* stop_gained 1.00 0
X:64192928:T L120* stop_gained 1.00 0
X:64192614:A R225* stop_gained 1.00 0
X:64192608:A E227* stop_gained 1.00 0
X:64190752:C Y845* stop_gained 1.00 0
X:64190752:T Y845* stop_gained 1.00 0
X:64193259:A Q10* stop_gained 1.00 0
X:64191021:A E756* stop_gained 1.00 0
X:64193172:A G39* stop_gained 1.00 0
X:64192842:A G149* stop_gained 1.00 0
X:64192650:A Q213* stop_gained 1.00 0
X:64191660:A E543* stop_gained 1.00 0
X:64191871:T Y472* stop_gained 1.00 0
X:64191871:C Y472* stop_gained 1.00 0
X:64190001:A Q1096* stop_gained 1.00 0
X:64192575:A K238* stop_gained 1.00 0
X:64191709:T Y526* stop_gained 1.00 0
X:64191709:C Y526* stop_gained 1.00 0
X:64191438:A E617* stop_gained 1.00 0
X:64190258:C S1010* stop_gained 1.00 0
X:64190258:T S1010* stop_gained 1.00 0
X:64189896:A G1131* stop_gained 1.00 0
X:64191787:T Y500* stop_gained 1.00 0
X:64191787:C Y500* stop_gained 1.00 0
X:64193274:A K5* stop_gained 1.00 0
X:64192557:A E244* stop_gained 1.00 0
X:64190348:T L980* stop_gained 1.00 0
X:64192204:T C361* stop_gained 1.00 0
X:64192128:A E387* stop_gained 1.00 0
X:64190010:A E1093* stop_gained 1.00 0
X:64191330:A E653* stop_gained 1.00 0
X:64192953:A E112* stop_gained 1.00 0
X:64191087:A E734* stop_gained 1.00 0
X:64191168:A G707* stop_gained 1.00 0
X:64192911:A Q126* stop_gained 1.00 0
X:64192058:T W410* stop_gained 1.00 0
X:64190395:T C964* stop_gained 1.00 0
X:64190511:A E926* stop_gained 1.00 0
X:64192533:A K252* stop_gained 1.00 0
X:64189953:A E1112* stop_gained 1.00 0
X:64190478:A E937* stop_gained 1.00 0
X:64192695:A E198* stop_gained 1.00 0
X:64192912:T C125* stop_gained 1.00 0
X:64190555:T L911* stop_gained 1.00 0
X:64192137:A E384* stop_gained 1.00 0
X:64190320:C Y989* stop_gained 1.00 0
X:64190320:T Y989* stop_gained 1.00 0
X:64191650:T L546* stop_gained 1.00 0
X:64192110:A E393* stop_gained 1.00 0
X:64190538:A E917* stop_gained 1.00 0
X:64191018:A E757* stop_gained 1.00 0
X:64190366:T W974* stop_gained 1.00 0
X:64191378:A E637* stop_gained 1.00 0
X:64192923:A E122* stop_gained 1.00 0
X:64193162:C S42* stop_gained 1.00 0
X:64193162:T S42* stop_gained 1.00 0
X:64192068:A E407* stop_gained 1.00 0
X:64191372:A Q639* stop_gained 1.00 0
X:64191160:T C709* stop_gained 1.00 0
X:64191249:A G680* stop_gained 1.00 0
X:64192070:C L406* stop_gained 1.00 0
X:64192070:T L406* stop_gained 1.00 0
X:64192632:A E219* stop_gained 1.00 0
X:64193061:A G76* stop_gained 1.00 0
X:64191302:T S662* stop_gained 1.00 0
X:64191302:C S662* stop_gained 1.00 0
X:64190142:A R1049* stop_gained 1.00 0
X:64191324:A Q655* stop_gained 1.00 0
X:64192398:A E297* stop_gained 1.00 0
X:64193184:A E35* stop_gained 1.00 0
X:64192476:A Q271* stop_gained 1.00 0
X:64192063:T Y408* stop_gained 1.00 0
X:64192063:C Y408* stop_gained 1.00 0
X:64191015:A E758* stop_gained 1.00 0
X:64192470:A K273* stop_gained 1.00 0
X:64192192:T Y365* stop_gained 1.00 0
X:64192192:C Y365* stop_gained 1.00 0
X:64191393:A E632* stop_gained 1.00 0
X:64192658:T S210* stop_gained 1.00 0
X:64192658:C S210* stop_gained 1.00 0
X:64193199:A K30* stop_gained 1.00 0
X:64190517:A Q924* stop_gained 1.00 0
X:64190529:A E920* stop_gained 1.00 0
X:64191090:A Q733* stop_gained 1.00 0
X:64192877:T L137* stop_gained 1.00 0
X:64192875:A E138* stop_gained 1.00 0
X:64192671:A E206* stop_gained 1.00 0
X:64192107:A E394* stop_gained 1.00 0
X:64190178:A Q1037* stop_gained 1.00 0
X:64190172:A Q1039* stop_gained 1.00 0
X:64189958:C S1110* stop_gained 1.00 0
X:64189958:T S1110* stop_gained 1.00 0
X:64191202:T W695* stop_gained 1.00 0
X:64190763:A E842* stop_gained 1.00 0
X:64192919:C L123* stop_gained 1.00 0
X:64192919:T L123* stop_gained 1.00 0
X:64192143:A E382* stop_gained 1.00 0
X:64192968:A E107* stop_gained 1.00 0
X:64192623:A Q222* stop_gained 1.00 0
X:64191180:A K703* stop_gained 1.00 0
X:64191726:A G521* stop_gained 1.00 0
X:64191612:A E559* stop_gained 1.00 0
X:64191153:A K712* stop_gained 1.00 0
X:64193130:A K53* stop_gained 1.00 0
X:64192512:A E259* stop_gained 1.00 0
X:64191453:A E612* stop_gained 1.00 0
X:64192047:A Q414* stop_gained 1.00 0
X:64192425:A E288* stop_gained 1.00 0
X:64191558:A Q577* stop_gained 1.00 0
X:64192833:A E152* stop_gained 1.00 0
X:64191528:A E587* stop_gained 1.00 0
X:64190031:A Q1086* stop_gained 1.00 0
X:64192818:A E157* stop_gained 1.00 0
X:64192086:A E401* stop_gained 1.00 0
X:64191203:T W695* stop_gained 1.00 0
X:64192122:A E389* stop_gained 1.00 0
X:64190436:A E951* stop_gained 1.00 0
X:64192797:A K164* stop_gained 1.00 0
X:64190118:A E1057* stop_gained 1.00 0
X:64192830:A K153* stop_gained 1.00 0
X:64190580:A E903* stop_gained 1.00 0
X:64191006:A K761* stop_gained 1.00 0
X:64191072:A G739* stop_gained 1.00 0
X:64190404:T W961* stop_gained 1.00 0
X:64192131:A E386* stop_gained 1.00 0
X:64190613:A R892* stop_gained 1.00 0
X:64190405:T W961* stop_gained 1.00 0
X:64190745:A K848* stop_gained 1.00 0
X:64192704:A K195* stop_gained 1.00 0
X:64191325:C Y654* stop_gained 1.00 0
X:64191325:T Y654* stop_gained 1.00 0
X:64192140:A E383* stop_gained 1.00 0
X:64191581:T L569* stop_gained 1.00 0
X:64192104:A E395* stop_gained 1.00 0
X:64189956:A K1111* stop_gained 1.00 0
X:64191363:A E642* stop_gained 1.00 0
X:64193067:A G74* stop_gained 1.00 0
X:64190667:A G874* stop_gained 1.00 0
X:64190550:A Q913* stop_gained 1.00 0
X:64192440:A E283* stop_gained 1.00 0
X:64190185:T Y1034* stop_gained 1.00 0
X:64191075:A G738* stop_gained 1.00 0
X:64190185:C Y1034* stop_gained 1.00 0
X:64192500:A E263* stop_gained 1.00 0
X:64191342:A K649* stop_gained 1.00 0
X:64192950:A G113* stop_gained 1.00 0
X:64193268:A E7* stop_gained 1.00 0
X:64192089:A E400* stop_gained 1.00 0
X:64192716:A E191* stop_gained 1.00 0
X:64192242:A Q349* stop_gained 1.00 0
X:64191147:A Q714* stop_gained 1.00 0
X:64190316:A Q991* stop_gained 1.00 0
X:64191239:T S683* stop_gained 1.00 0
X:64191239:C S683* stop_gained 1.00 0
X:64191102:A E729* stop_gained 1.00 0
X:64192722:A Q189* stop_gained 1.00 0
X:64190504:C S928* stop_gained 1.00 0
X:64191760:T Y509* stop_gained 1.00 0
X:64192083:A E402* stop_gained 1.00 0
X:64190504:T S928* stop_gained 1.00 0
X:64191760:C Y509* stop_gained 1.00 0
X:64191561:A E576* stop_gained 1.00 0
X:64189995:A Q1098* stop_gained 1.00 0
X:64191009:A E760* stop_gained 1.00 0
X:64192986:A E101* stop_gained 1.00 0
X:64190574:A E905* stop_gained 1.00 0
X:64190523:A Q922* stop_gained 1.00 0
X:64191129:A Q720* stop_gained 1.00 0
X:64193283:A E2* stop_gained 1.00 0
X:64191573:A E572* stop_gained 1.00 0
X:64192857:A K144* stop_gained 1.00 0
X:64190964:A E775* stop_gained 1.00 0
X:64190499:A E930* stop_gained 1.00 0
X:64190468:T W940* stop_gained 1.00 0
X:64190774:T L838* stop_gained 1.00 0
X:64192746:A K181* stop_gained 1.00 0
X:64190826:A K821* stop_gained 1.00 0
X:64191668:C L540* stop_gained 1.00 0
X:64190709:A Q860* stop_gained 1.00 0
X:64190676:A R871* stop_gained 1.00 0
X:64191483:A E602* stop_gained 1.00 0
X:64191575:T W571* stop_gained 1.00 0
X:64191584:T L568* stop_gained 1.00 0
X:64191615:A E558* stop_gained 1.00 0
X:64191618:A E557* stop_gained 1.00 0
X:64191668:T L540* stop_gained 1.00 0
X:64190216:T S1024* stop_gained 1.00 0
X:64190216:C S1024* stop_gained 1.00 0
X:64193160:A E43* stop_gained 1.00 0
X:64191546:A Q581* stop_gained 1.00 0
X:64190817:A E824* stop_gained 1.00 0
X:64191574:T W571* stop_gained 1.00 0
X:64193127:A K54* stop_gained 1.00 0
X:64192443:A E282* stop_gained 1.00 0
X:64190276:T S1004* stop_gained 1.00 0
X:64190276:C S1004* stop_gained 1.00 0
X:64193007:A K94* stop_gained 1.00 0
X:64192287:A E334* stop_gained 1.00 0
X:64192788:A K167* stop_gained 1.00 0
X:64192316:T S324* stop_gained 1.00 0
X:64192329:A K320* stop_gained 1.00 0
X:64192352:T L312* stop_gained 1.00 0
X:64192191:A Q366* stop_gained 1.00 0
X:64192188:A G367* stop_gained 1.00 0
X:64190978:T S770* stop_gained 1.00 0
X:64192313:T L325* stop_gained 1.00 0
X:64191926:T L454* stop_gained 1.00 0
X:64191918:A Q457* stop_gained 1.00 0
X:64191909:A Q460* stop_gained 1.00 0
X:64191906:A Q461* stop_gained 1.00 0
X:64191882:A E469* stop_gained 1.00 0
X:64191855:A G478* stop_gained 1.00 0
X:64192284:A Q335* stop_gained 1.00 0
X:64192316:C S324* stop_gained 1.00 0
X:64191783:A G502* stop_gained 1.00 0
X:64191768:A E507* stop_gained 1.00 0
X:64192815:A K158* stop_gained 1.00 0
X:64190976:A Q771* stop_gained 1.00 0
X:64190978:C S770* stop_gained 1.00 0
X:64190832:A E819* stop_gained 1.00 0
X:64190906:C S794* stop_gained 1.00 0
X:64190906:T S794* stop_gained 1.00 0
X:64190793:A E832* stop_gained 1.00 0
X:64191759:A E510* stop_gained 1.00 0
X:64190696:T W864* stop_gained 1.00 0
X:64192740:A K183* stop_gained 1.00 0
X:64190695:T W864* stop_gained 1.00 0
X:64193040:A K83* stop_gained 1.00 0
X:64193028:A K87* stop_gained 1.00 0
X:64190820:A E823* stop_gained 1.00 0
X:64190883:A E802* stop_gained 1.00 0
X:64191594:A Q565* stop_gained 1.00 0
X:64193097:A K64* stop_gained 1.00 0
X:64192218:A K357* stop_gained 1.00 0
X:64192176:A E371* stop_gained 1.00 0
X:64191933:A E452* stop_gained 1.00 0
X:64191834:A E485* stop_gained 1.00 0
X:64192896:A Q131* stop_gained 1.00 0
X:64193013:A K92* stop_gained 1.00 0
X:64193025:A K88* stop_gained 1.00 0
X:64193052:A K79* stop_gained 1.00 0
X:64193100:A K63* stop_gained 1.00 0
X:64193115:A K58* stop_gained 1.00 0
X:64190895:A Q798* stop_gained 1.00 0
X:64190844:A E815* stop_gained 1.00 0
X:64192791:A K166* stop_gained 1.00 0
X:64191024:A E755* stop_gained 1.00 0
X:64190589:A E900* stop_gained 1.00 0
X:64192779:A K170* stop_gained 1.00 0
X:64190772:A E839* stop_gained 1.00 0
X:64192725:A E188* stop_gained 1.00 0
X:64190808:A E827* stop_gained 1.00 0
X:64190669:T L873* stop_gained 1.00 0
X:64190481:A E936* stop_gained 1.00 0
X:64192166:T L374* stop_gained 1.00 0
X:64191033:A E752* stop_gained 1.00 0
X:64190718:A R857* stop_gained 1.00 0
X:64190331:A Q986* stop_gained 1.00 0
X:64193211:A E26* stop_gained 1.00 0
X:64192487:T S267* stop_gained 1.00 0
X:64192487:C S267* stop_gained 1.00 0
X:64191332:T L652* stop_gained 1.00 0
X:64191041:C S749* stop_gained 1.00 0
X:64191041:T S749* stop_gained 1.00 0
X:64191332:C L652* stop_gained 1.00 0
X:64191345:A E648* stop_gained 1.00 0
X:64191003:A E762* stop_gained 1.00 0
X:64190061:A K1076* stop_gained 1.00 0
X:64191591:A K566* stop_gained 1.00 0
X:64189941:A Q1116* stop_gained 1.00 0
X:64191264:A Q675* stop_gained 1.00 0
X:64191311:T L659* stop_gained 1.00 0
X:64191311:C L659* stop_gained 1.00 0
X:64191120:A Q723* stop_gained 1.00 0
X:64192239:A R350* stop_gained 1.00 0
X:64191468:A E607* stop_gained 1.00 0
X:64191052:C Y745* stop_gained 1.00 0
X:64191052:T Y745* stop_gained 1.00 0
X:64191839:C S483* stop_gained 1.00 0
X:64191839:T S483* stop_gained 1.00 0
X:64191171:A E706* stop_gained 1.00 0
X:64191156:A K711* stop_gained 1.00 0
X:64192146:A E381* stop_gained 1.00 0
X:64190484:A E935* stop_gained 1.00 0
X:64191183:A E702* stop_gained 1.00 0
X:64190282:C S1002* stop_gained 1.00 0
X:64190282:T S1002* stop_gained 1.00 0
X:64191543:A E582* stop_gained 1.00 0
X:64191624:A E555* stop_gained 1.00 0
X:64191275:C S671* stop_gained 1.00 0
X:64191275:T S671* stop_gained 1.00 0
X:64190487:A E934* stop_gained 1.00 0
X:64193208:A K27* stop_gained 1.00 0
X:64192863:A R142* stop_gained 1.00 0
X:64190067:A Q1074* stop_gained 1.00 0
X:64190472:A E939* stop_gained 1.00 0
X:64191769:C Y506* stop_gained 1.00 0
X:64191769:T Y506* stop_gained 1.00 0
X:64191687:A E534* stop_gained 1.00 0
X:64190352:A Q979* stop_gained 1.00 0
In silico saturation mutagenesis
Alt text Show figure caption
Cancer type Selected cancer type Mutational discovery Index Feature Complexity
(COREAD) Colorectal adenocarcinoma COREAD 0.57 0.04