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ZXDA has not been detected as a mutational cancer driver

ZXDA
Ensembl id ENSG00000198205
Mutated samples
Coding Sequence 52 (0.8%)
Protein Affecting 33 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ZXDA gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Uterine corpus endometrioid carcinoma No 7 5 2.17
Lung squamous cell carcinoma No 5 4 2.30
Head and neck squamous cell carcinoma No 5 4 1.07
Lung adenocarcinoma No 8 3 0.77
Cutaneous melanoma No 8 3 0.81
Esophageal carcinoma No 3 3 2.05
Serous ovarian adenocarcinoma No 2 2 0.63
Stomach adenocarcinoma No 3 2 1.24
Colorectal adenocarcinoma No 2 2 0.87
Breast carcinoma No 2 1 0.09
Chronic lymphocytic leukemia No 1 1 0.34
Small cell lung carcinoma No 1 1 1.45
Diffuse B cell lymphoma No 1 1 4.35
Glioblastoma multiforme No 2 1 0.26
Renal clear cell carcinoma No 1 0 0.00
Lower grade glioma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence