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ZSCAN20 has not been detected as a mutational cancer driver

ZSCAN20
Ensembl id ENSG00000121903
Mutated samples
Coding Sequence 61 (0.9%)
Protein Affecting 45 (0.7%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ZSCAN20 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 23 14 3.79
Colorectal adenocarcinoma No 4 4 1.75
Lung adenocarcinoma No 3 3 0.77
Pancreas adenocarcinoma No 3 3 1.40
Renal clear cell carcinoma No 3 3 0.72
Uterine corpus endometrioid carcinoma No 5 3 1.30
Breast carcinoma No 3 2 0.17
Lung squamous cell carcinoma No 2 2 1.15
Thyroid carcinoma No 2 2 0.62
Serous ovarian adenocarcinoma No 2 2 0.63
Glioblastoma multiforme No 2 2 0.53
Esophageal carcinoma No 2 2 1.37
Bladder carcinoma No 1 1 1.02
Stomach adenocarcinoma No 2 1 0.62
Acute lymphocytic leukemia No 1 1 0.82
Lower grade glioma No 1 0 0.00
Small cell lung carcinoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence