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ZNF804A has not been detected as a mutational cancer driver

ZNF804A
Ensembl id ENSG00000170396
Mutated samples
Coding Sequence 254 (3.7%)
Protein Affecting 206 (3.0%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ZNF804A gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 88 69 18.70
Lung adenocarcinoma No 39 37 9.46
Lung squamous cell carcinoma No 21 17 9.77
Head and neck squamous cell carcinoma No 17 16 4.27
Stomach adenocarcinoma No 12 10 6.21
Small cell lung carcinoma No 10 10 14.49
Esophageal carcinoma No 9 7 4.79
Renal clear cell carcinoma No 6 6 1.44
Serous ovarian adenocarcinoma No 7 5 1.58
Colorectal adenocarcinoma No 7 5 2.18
Bladder carcinoma No 5 4 4.08
Non small cell lung carcinoma No 4 4 12.90
Glioblastoma multiforme No 4 4 1.06
Uterine corpus endometrioid carcinoma No 5 3 1.30
Breast carcinoma No 4 2 0.17
Pancreas adenocarcinoma No 2 2 0.93
Thyroid carcinoma No 2 2 0.62
Chronic lymphocytic leukemia No 8 2 0.69
Hepatocarcinoma No 2 1 1.11
Medulloblastoma No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence