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ZNF644 has not been detected as a mutational cancer driver

ZNF644
Ensembl id ENSG00000122482
Mutated samples
Coding Sequence 75 (1.1%)
Protein Affecting 51 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ZNF644 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Breast carcinoma No 9 8 0.70
Cutaneous melanoma No 11 6 1.63
Head and neck squamous cell carcinoma No 7 6 1.60
Lung adenocarcinoma No 8 5 1.28
Bladder carcinoma No 4 4 4.08
Uterine corpus endometrioid carcinoma No 7 4 1.74
Stomach adenocarcinoma No 6 4 2.48
Lung squamous cell carcinoma No 3 3 1.72
Prostate adenocarcinoma No 2 2 0.82
Renal clear cell carcinoma No 2 2 0.48
Small cell lung carcinoma No 3 2 2.90
Thyroid carcinoma No 1 1 0.31
Multiple myeloma No 2 1 1.45
Lower grade glioma No 1 1 0.59
Serous ovarian adenocarcinoma No 2 1 0.32
Glioblastoma multiforme No 3 1 0.26
Medulloblastoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence