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ZNF512 has not been detected as a mutational cancer driver

ZNF512
Ensembl id ENSG00000243943
Mutated samples
Coding Sequence 154 (2.3%)
Protein Affecting 31 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ZNF512 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 39 6 1.63
Breast carcinoma No 17 5 0.44
Uterine corpus endometrioid carcinoma No 13 5 2.17
Lung squamous cell carcinoma No 16 4 2.30
Head and neck squamous cell carcinoma No 15 4 1.07
Lung adenocarcinoma No 12 2 0.51
Prostate adenocarcinoma No 3 1 0.41
Thyroid carcinoma No 2 1 0.31
Serous ovarian adenocarcinoma No 5 1 0.32
Stomach adenocarcinoma No 8 1 0.62
Small cell lung carcinoma No 4 1 1.45
Bladder carcinoma No 9 0 0.00
Medulloblastoma No 1 0 0.00
Renal clear cell carcinoma No 1 0 0.00
Neuroblastoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Colorectal adenocarcinoma No 2 0 0.00
Glioblastoma multiforme No 3 0 0.00
Esophageal carcinoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence