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ZNF197 has not been detected as a mutational cancer driver

ZNF197
Ensembl id ENSG00000186448
Mutated samples
Coding Sequence 72 (1.1%)
Protein Affecting 36 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ZNF197 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 25 13 3.52
Lung adenocarcinoma No 5 3 0.77
Lung squamous cell carcinoma No 3 3 1.72
Serous ovarian adenocarcinoma No 3 3 0.95
Esophageal carcinoma No 7 3 2.05
Bladder carcinoma No 3 2 2.04
Uterine corpus endometrioid carcinoma No 3 2 0.87
Prostate adenocarcinoma No 3 1 0.41
Hepatocarcinoma No 2 1 1.11
Breast carcinoma No 2 1 0.09
Multiple myeloma No 1 1 1.45
Colorectal adenocarcinoma No 2 1 0.44
Head and neck squamous cell carcinoma No 4 1 0.27
Glioblastoma multiforme No 1 1 0.26
Acute myeloid leukemia No 1 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
Lower grade glioma No 1 0 0.00
Stomach adenocarcinoma No 2 0 0.00
Small cell lung carcinoma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence