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ZNF142 has not been detected as a mutational cancer driver

ZNF142
Ensembl id ENSG00000115568
Mutated samples
Coding Sequence 121 (1.8%)
Protein Affecting 54 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ZNF142 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 32 13 3.52
Breast carcinoma No 11 6 0.52
Lung adenocarcinoma No 11 5 1.28
Uterine corpus endometrioid carcinoma No 6 5 2.17
Head and neck squamous cell carcinoma No 8 4 1.07
Prostate adenocarcinoma No 4 3 1.23
Stomach adenocarcinoma No 7 3 1.86
Colorectal adenocarcinoma No 5 3 1.31
Lung squamous cell carcinoma No 4 2 1.15
Small cell lung carcinoma No 3 2 2.90
Glioblastoma multiforme No 6 2 0.53
Bladder carcinoma No 5 1 1.02
Renal clear cell carcinoma No 4 1 0.24
Thyroid carcinoma No 2 1 0.31
Serous ovarian adenocarcinoma No 6 1 0.32
Diffuse B cell lymphoma No 1 1 4.35
Esophageal carcinoma No 3 1 0.68
Medulloblastoma No 1 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence