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ZMPSTE24 has not been detected as a mutational cancer driver

ZMPSTE24
Ensembl id ENSG00000084073
Mutated samples
Coding Sequence 29 (0.4%)
Protein Affecting 22 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ZMPSTE24 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 6 6 1.63
Uterine corpus endometrioid carcinoma No 6 5 2.17
Lung adenocarcinoma No 3 2 0.51
Breast carcinoma No 2 2 0.17
Lung squamous cell carcinoma No 2 2 1.15
Renal clear cell carcinoma No 3 2 0.48
Bladder carcinoma No 1 1 1.02
Lower grade glioma No 1 1 0.59
Stomach adenocarcinoma No 2 1 0.62
Hepatocarcinoma No 2 0 0.00
Medulloblastoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence