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ZDBF2 has not been detected as a mutational cancer driver

ZDBF2
Ensembl id ENSG00000204186
Mutated samples
Coding Sequence 195 (2.9%)
Protein Affecting 157 (2.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ZDBF2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 75 60 16.26
Lung adenocarcinoma No 16 15 3.84
Breast carcinoma No 20 15 1.31
Lung squamous cell carcinoma No 17 14 8.05
Stomach adenocarcinoma No 11 7 4.35
Glioblastoma multiforme No 7 7 1.85
Renal clear cell carcinoma No 7 6 1.44
Head and neck squamous cell carcinoma No 6 6 1.60
Small cell lung carcinoma No 4 4 5.80
Colorectal adenocarcinoma No 7 4 1.75
Uterine corpus endometrioid carcinoma No 3 3 1.30
Serous ovarian adenocarcinoma No 4 3 0.95
Esophageal carcinoma No 4 3 2.05
Prostate adenocarcinoma No 2 2 0.82
Bladder carcinoma No 2 2 2.04
Medulloblastoma No 1 1 0.48
Thyroid carcinoma No 1 1 0.31
Neuroblastoma No 1 1 0.48
Chronic lymphocytic leukemia No 3 1 0.34
Multiple myeloma No 1 1 1.45
Lower grade glioma No 2 1 0.59
Hepatocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence