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ZCCHC12 has not been detected as a mutational cancer driver

ZCCHC12
Ensembl id ENSG00000174460
Mutated samples
Coding Sequence 50 (0.7%)
Protein Affecting 40 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ZCCHC12 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 9 7 1.90
Lung adenocarcinoma No 5 5 1.28
Breast carcinoma No 5 5 0.44
Lung squamous cell carcinoma No 5 4 2.30
Uterine corpus endometrioid carcinoma No 3 3 1.30
Lower grade glioma No 3 3 1.78
Head and neck squamous cell carcinoma No 3 3 0.80
Renal clear cell carcinoma No 2 2 0.48
Stomach adenocarcinoma No 3 2 1.24
Small cell lung carcinoma No 2 2 2.90
Prostate adenocarcinoma No 1 1 0.41
Colorectal adenocarcinoma No 3 1 0.44
Glioblastoma multiforme No 1 1 0.26
Esophageal carcinoma No 1 1 0.68
Bladder carcinoma No 2 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence