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ZC3H12B has not been detected as a mutational cancer driver

ZC3H12B
Ensembl id ENSG00000102053
Mutated samples
Coding Sequence 53 (0.8%)
Protein Affecting 42 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ZC3H12B gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 10 8 2.05
Cutaneous melanoma No 9 7 1.90
Uterine corpus endometrioid carcinoma No 6 6 2.61
Breast carcinoma No 5 4 0.35
Lung squamous cell carcinoma No 4 3 1.72
Chronic lymphocytic leukemia No 2 2 0.69
Lower grade glioma No 2 2 1.18
Head and neck squamous cell carcinoma No 4 2 0.53
Glioblastoma multiforme No 4 2 0.53
Bladder carcinoma No 1 1 1.02
Pancreas adenocarcinoma No 1 1 0.47
Thyroid carcinoma No 1 1 0.31
Neuroblastoma No 1 1 0.48
Colorectal adenocarcinoma No 1 1 0.44
Esophageal carcinoma No 2 1 0.68
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence