ZC3H11A mutations in 9 cancer types possibly contribute to the detection of the gene in the PAN-cancer anlaysis:: Lung squamous cell carcinoma, Thyroid carcinoma, Cutaneous melanoma, Uterine corpus endometrioid carcinoma, Stomach adenocarcinoma, Small cell lung carcinoma, Colorectal adenocarcinoma, Head and neck squamous cell carcinoma, Esophageal carcinoma

Ensembl id ENSG00000058673
Mutated samples
Coding Sequence 46 (0.7%)
Protein Affecting 39 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ZC3H11A gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma Yes 9 6 1.63
Head and neck squamous cell carcinoma Yes 4 4 1.07
Lung squamous cell carcinoma Yes 3 3 1.72
Stomach adenocarcinoma Yes 4 3 1.86
Thyroid carcinoma Yes 3 2 0.62
Uterine corpus endometrioid carcinoma Yes 3 2 0.87
Small cell lung carcinoma Yes 2 2 2.90
Colorectal adenocarcinoma Yes 2 2 0.87
Esophageal carcinoma Yes 2 2 1.37
Lung adenocarcinoma No 6 6 1.53
Breast carcinoma No 4 4 0.35
Prostate adenocarcinoma No 1 1 0.41
Renal clear cell carcinoma No 1 1 0.24
Non small cell lung carcinoma No 1 1 3.23
Glioblastoma multiforme No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence