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ZBTB38 has not been detected as a mutational cancer driver

ZBTB38
Ensembl id ENSG00000177311
Mutated samples
Coding Sequence 72 (1.1%)
Protein Affecting 45 (0.7%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ZBTB38 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 13 8 2.17
Renal clear cell carcinoma No 8 6 1.44
Head and neck squamous cell carcinoma No 6 5 1.33
Lung squamous cell carcinoma No 6 4 2.30
Uterine corpus endometrioid carcinoma No 7 4 1.74
Stomach adenocarcinoma No 8 4 2.48
Breast carcinoma No 5 3 0.26
Serous ovarian adenocarcinoma No 3 3 0.95
Lung adenocarcinoma No 4 2 0.51
Bladder carcinoma No 3 2 2.04
Prostate adenocarcinoma No 1 1 0.41
Multiple myeloma No 1 1 1.45
Small cell lung carcinoma No 1 1 1.45
Glioblastoma multiforme No 2 1 0.26
Medulloblastoma No 2 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence