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ZBTB20 has not been detected as a mutational cancer driver

ZBTB20
Ensembl id ENSG00000181722
Mutated samples
Coding Sequence 94 (1.4%)
Protein Affecting 58 (0.9%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ZBTB20 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 17 9 2.44
Stomach adenocarcinoma No 12 9 5.59
Lung adenocarcinoma No 8 6 1.53
Lower grade glioma No 7 6 3.55
Lung squamous cell carcinoma No 8 4 2.30
Serous ovarian adenocarcinoma No 4 4 1.27
Head and neck squamous cell carcinoma No 5 4 1.07
Esophageal carcinoma No 6 4 2.74
Renal clear cell carcinoma No 4 3 0.72
Breast carcinoma No 3 2 0.17
Uterine corpus endometrioid carcinoma No 4 2 0.87
Non small cell lung carcinoma No 4 2 6.45
Bladder carcinoma No 2 1 1.02
Medulloblastoma No 1 1 0.48
Glioblastoma multiforme No 1 1 0.26
Hepatocarcinoma No 1 0 0.00
Pancreas adenocarcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 6 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence