IntOGen - ZBTB20 gene cancer mutations

ZBTB20 is detected as a mutational cancer driver

ZBTB20 reports

Methods
Mutation distribution

Gene details

ZBTB20
Ensembl ID ENSG00000181722 Transcript ID ENST00000675478 Protein ID ENSP00000501561
Cancer types where is driver 1 Cohorts where is driver 1 Mutated samples 19 Mutations 448
Mode of action Loss of function
Known driver False

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence