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WWC3 has not been detected as a mutational cancer driver

WWC3
Ensembl id ENSG00000047644
Mutated samples
Coding Sequence 82 (1.2%)
Protein Affecting 62 (0.9%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all WWC3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 12 10 2.71
Stomach adenocarcinoma No 11 10 6.21
Breast carcinoma No 12 8 0.70
Uterine corpus endometrioid carcinoma No 7 6 2.61
Lung adenocarcinoma No 5 4 1.02
Lung squamous cell carcinoma No 4 4 2.30
Glioblastoma multiforme No 5 4 1.06
Lower grade glioma No 3 3 1.78
Serous ovarian adenocarcinoma No 5 3 0.95
Head and neck squamous cell carcinoma No 3 3 0.80
Small cell lung carcinoma No 2 2 2.90
Prostate adenocarcinoma No 1 1 0.41
Neuroblastoma No 1 1 0.48
Non small cell lung carcinoma No 1 1 3.23
Esophageal carcinoma No 2 1 0.68
Acute lymphocytic leukemia No 1 1 0.82
Bladder carcinoma No 2 0 0.00
Renal clear cell carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Colorectal adenocarcinoma No 3 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence