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WRAP73 has not been detected as a mutational cancer driver

WRAP73
Ensembl id ENSG00000116213
Mutated samples
Coding Sequence 38 (0.6%)
Protein Affecting 17 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all WRAP73 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Breast carcinoma No 2 2 0.17
Cutaneous melanoma No 10 2 0.54
Uterine corpus endometrioid carcinoma No 6 2 0.87
Stomach adenocarcinoma No 3 2 1.24
Small cell lung carcinoma No 2 2 2.90
Lung adenocarcinoma No 1 1 0.26
Lung squamous cell carcinoma No 2 1 0.57
Renal clear cell carcinoma No 3 1 0.24
Thyroid carcinoma No 1 1 0.31
Colorectal adenocarcinoma No 1 1 0.44
Glioblastoma multiforme No 2 1 0.26
Acute lymphocytic leukemia No 1 1 0.82
Bladder carcinoma No 2 0 0.00
Head and neck squamous cell carcinoma No 1 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence