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WDTC1 has not been detected as a mutational cancer driver

WDTC1
Ensembl id ENSG00000142784
Mutated samples
Coding Sequence 49 (0.7%)
Protein Affecting 35 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all WDTC1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 10 5 1.36
Uterine corpus endometrioid carcinoma No 6 5 2.17
Lung adenocarcinoma No 4 4 1.02
Stomach adenocarcinoma No 5 4 2.48
Head and neck squamous cell carcinoma No 5 4 1.07
Bladder carcinoma No 2 2 2.04
Prostate adenocarcinoma No 1 1 0.41
Hepatocarcinoma No 1 1 1.11
Lung squamous cell carcinoma No 2 1 0.57
Renal clear cell carcinoma No 2 1 0.24
Thyroid carcinoma No 1 1 0.31
Serous ovarian adenocarcinoma No 1 1 0.32
Small cell lung carcinoma No 1 1 1.45
Colorectal adenocarcinoma No 3 1 0.44
Glioblastoma multiforme No 1 1 0.26
Esophageal carcinoma No 2 1 0.68
Acute lymphocytic leukemia No 1 1 0.82
Chronic lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence