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WDR63 has not been detected as a mutational cancer driver

WDR63
Ensembl id ENSG00000162643
Mutated samples
Coding Sequence 97 (1.4%)
Protein Affecting 44 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all WDR63 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 12 9 2.44
Lung adenocarcinoma No 15 6 1.53
Head and neck squamous cell carcinoma No 9 6 1.60
Glioblastoma multiforme No 9 5 1.32
Breast carcinoma No 7 3 0.26
Lung squamous cell carcinoma No 9 3 1.72
Stomach adenocarcinoma No 3 3 1.86
Uterine corpus endometrioid carcinoma No 5 2 0.87
Serous ovarian adenocarcinoma No 2 2 0.63
Medulloblastoma No 1 1 0.48
Renal clear cell carcinoma No 8 1 0.24
Neuroblastoma No 1 1 0.48
Chronic lymphocytic leukemia No 4 1 0.34
Lower grade glioma No 1 1 0.59
Prostate adenocarcinoma No 1 0 0.00
Hepatocarcinoma No 1 0 0.00
Bladder carcinoma No 1 0 0.00
Multiple myeloma No 2 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Colorectal adenocarcinoma No 3 0 0.00
Esophageal carcinoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence